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Selection of Optimal Biotic Elicitor on Tropane Alkaloid Production of Hairy Roots in Scopolia parviflora Nakai  

Jung, Hee-Young (Division of Forest Science, Gyeongsang National University)
Kang, Seung-Mi (Division of Forest Science, Gyeongsang National University)
Kang, Young-Min (Division of Forest Science, Gyeongsang National University)
Kim, Yong-Duk (Division of Forest Science, Gyeongsang National University)
Yang, Jae-Kyung (Division of Forest Science, Gyeongsang National University)
Chung, Young-Gwan (Division of Forest Science, Gyeongsang National University)
Choi, Myung-Suk (Division of Forest Science, Gyeongsang National University)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.5, 2003 , pp. 358-363 More about this Journal
Abstract
ScopoIamine and hyoscyamine which belong to tropane alkaloids are the pharmaceutically valuable anticholinergic drugs. In order to increase the productivities, the effects of elicitation were investigated during hairy root cultures of Scopolia. parviflora. Biotic elicitors originated from 3 fungi and 1 yeast were prepared as homogenate and supernatant and added to 3-week-old cultures. Both of homogenate and supernatant of Candida albicans elicitors increased the scopolamine production. The production of hyoscyamine was enhanced by homogenate of Fusarium solani and supernatant of C. albicans. Most of the other fungal elicitors were also improved on the tropane alkaloid production compared to non-treatment. Among the elicitors tested, C. albicans was proved the optimal biotic elicitor on tropane alkaloids production. These results will be served mass production of tropane alkaloids by large-scale production.
Keywords
tropane alkaloids; Scopolia parviflora; biotic elicitor; fungal elicitor;
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