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Effect of Fruits of Hovenia dulcis Thunb. on Learning Ability of Ethanol-induced Rats  

Lim, Jong-Pil (Department of Oriental Pharmacy, Woosuk University)
Cui, Xun (Department of Oriental Pharmacy, Woosuk University)
Song, Jeong-Mo (College of Oriental Medicine, Woosuk University)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.3, 2003 , pp. 232-235 More about this Journal
Abstract
To investigate effect of fruits of Hovenia dulcis Thunb. on learning ability of ethanol-induced rats, we divided rats into 3 groups; normal, control and sample groups. Control group administered ethanol at a dose 3 g/kg bw. (25 v/v %), while sample group administered the water extract of fruits of Hovenia dulcis Thunb. 30 min. before treating same dose of ethanol as control group orally. All groups were subjected to trials of straight channel on the 1st day and to those of multiple T-maze during the following 3 days. The time required in normal group for the straight channel of the 2nd and the 3rd trials was significantly shorter than that of the 1st, while control group showed no significance. In the time required for the multiple T-maze trials of control group, there were no significance. But in the straight channel or multiple T-maze trials, the sample group showed significant decrease in the time required against control group, and also showed significant decrease in the number of selecting errors.
Keywords
Hovenia dulcis; learning ability; T-maze; ethanol;
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