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Comparison of biological activities of essential oils from Foeniculum vulgare Mill, Boswellia carteii Birew and Juniperus rigida Sieb. by a supercritical fluid extraction system  

Lee, Hyun-Soo (School of Biotechnology and Bioengineering, Kangwon National University)
Mun, Chul-Hyung (School of Biotechnology and Bioengineering, Kangwon National University)
Park, Jin-Hong (School of Biotechnology and Bioengineering, Kangwon National University)
Kim, Dae-Ho (School of Biotechnology and Bioengineering, Kangwon National University)
Yoo, Jae-Eun (O.Z. Tech)
Park, Young-Sik (O.Z. Tech)
Ryu, Lee-Ha (JINRO Ltd.)
Choi, Keun-Pyo (School of Biotechnology and Bioengineering, Kangwon National University)
Lee, Hyeon-Yong (School of Biotechnology and Bioengineering, Kangwon National University)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.2, 2003 , pp. 115-121 More about this Journal
Abstract
Essential oils from Fennel fruit(Foeniculum vulgare Mill), Olibanum resin(Boswellia carteii Birew) and Needl Juniperus stem(Juniperus rigida Sieb.) were extracted by a supercritical fluid extraction system(SFE) and biological activity of each essential oils were observed. SFE technique was applied for the isolation and purification of nonpolar biologically active essential oils from each samples. The quantitative analysis of essential oils was carried out by gas chromatography-mass spectrometer(GC/MS). About 60% of the growth of AGS and A549 cells were inhibited by adding 1.0g/l of the crude essential oils and below 40% was observed by the control. Cytotoxicity on human normal lung cell(HEL299) was scored as $15{\sim}18%$ for the crude essential oils and 12% for control, respectively. It meant that the essential oils were more effective than the control in anti-mutagenecity tested by CHO V79 cells. The effect of the essential oils on the growth of nerve cells, PC12 was observed as follows: The viable cell density was about two times higher than control.
Keywords
Foeniculum vulgare Mill; Boswellia carteii Birew; Juniperus rigida Sieb.; essential oil; supercritical fluid extraction system;
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