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Screening of Plant Resources of anti-viral activity  

Kwon, Dur-Han (Kor. Res. Ins. of Biosci. & Biotech.)
Kim, Man-Bae (Gyeongnam Agri. Res. & Ext. Services)
Yoon, Do-Young (Kor. Res. Ins. of Biosci. & Biotech.)
Lee, Young-Hee (Kor. Res. Ins. of Biosci. & Biotech.)
Kim, Jae-Wha (Kor. Res. Ins. of Biosci. & Biotech.)
Lee, Hee-Gu (Kor. Res. Ins. of Biosci. & Biotech.)
Choi, In-Seong (Kor. Res. Ins. of Biosci. & Biotech.)
Lim, Jong-Seok (Kor. Res. Ins. of Biosci. & Biotech.)
Choe, Yong-Kyeung (Kor. Res. Ins. of Biosci. & Biotech.)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.1, 2003 , pp. 24-30 More about this Journal
Abstract
Aqueous extracts from eleven species of Korean medicinal plants were screened for antiviral activity against transmissble gastroenteritis virus (TGEV) and porcine epidemic diarrhae virus (PEDV). Seven of eleven plant extracts were found to have cytotoxicity for ST cells at the concentration of 1mg/ml, and ten extracts except Ephedra sinica were found to have non-cytotoxicity for Vero cells at the same concentration, Extracts of Zanthoxylum piperium, Cudrina tricuspidata, Clerodendron trichomum, Sophora flavescens, effectively inhibited TGEV, respectively. There were the antiviral activity against TGEV in the extracts of Glesdistsia sinensis, Euonymus alatus, Ficus carica, Solanum nigrum, Ephedra sinica, Xanthium strumarium, Acanthopanax seeliflorus in spite of their cytotoxicities. Nine extracts except Xanthium strumarium and Acanthopanax seeliflorus were found to have the antiviral activitity against PEDV. Extracts of Zanthoxylum piperium, Sophora flavescens was shown to have antiviral activities against both TGEV and PEDV.
Keywords
TGEV; PEDV; medicinal plants; antiviral;
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