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Isolation and Structure Elucidation of Radical Scavengers from Chrysanthemum boreale Makino  

Han, Wan-Soo (Department of Chemistry, Natural Science College, Mokwon University)
Publication Information
Korean Journal of Medicinal Crop Science / v.11, no.1, 2003 , pp. 1-4 More about this Journal
Abstract
Two antioxidative compounds in Chrysanthemum boreale were isolated by a bioassay using a 2, 2-diphenyl-1-picrydrazyl(DPPH) free radical. They were identified as apigenin, linarin(acacetin-7-O-rutinoside) on the basis of $^1H\;and\;^{13}C-NMR$ and MS data. The DPPH radical scavenging activity$(RC_{50}:\;13.3{\mu}g)$ of apigenin was similar to that of ${\alpha}-tocopherol\;(12.1{\mu}g)$ and L-ascorbic acid$(13.1{\mu}g)$
Keywords
Chrysanthemum boreale. 2; 2-diphenyl-1-picrydrazyl(DPPH); apigenin; linarin;
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