Transgenic Lettuce Expressing Chalcone Isomerase Gene of Chinese Cabbage Increased Levels of Flavonoids and Polyphenols |
Han, Eun-Hyang
(Department of Horticultural Biotechnology, Kyung Hee University)
Lee, Ji-Sun (Department of Horticultural Biotechnology, Kyung Hee University) Lee, Jae-Woong (Department of Horticultural Biotechnology, Kyung Hee University) Chung, In-Sik (Graduate School of Biotechnology & Plant Metabolism Research Center, Kyung Hee University) Lee, Youn-Hyung (Department of Horticultural Biotechnology, Kyung Hee University) |
1 | United States Department of Agriculture (USDA). 2007. USDA Database for the flavonoid content of selected foods. U.S. Depart. Agr. p. 51 |
2 | Van der Meer, I.M., M.E. Stam, A.J. van Tunen, J.N. Mol, and A.R. Stuitje. 1992. Antisense inhibition of flavonoid biosynthesis in petunia anthers results in male sterility. Plant Cell 4:253-262. DOI |
3 | Vaucheret, H. and M. Fagard. 2001. Transcriptional gene silencing in plants: Targets, inducers and regulators. Trends Genet. 17:29-35. DOI ScienceOn |
4 | Ylstra, B., A. Touraev, R.M. Moreno, E. Stoger, A.J. van Tunen, O. Vicente, J.N. Mol, and E. Heberle-Bors. 1992. Flavonols stimulate development, germination, and tube growth of tobacco pollen. Plant Physiol. 100:902-907. DOI ScienceOn |
5 | Lee, Z.A., H.Y. Kim, K.H. Chung, and Y.D. Park. 2004. Introduction of two types of human ferritin gene into lettuce plants. J. Kor. Soc. Hort. Sci. 45:330-335. |
6 | Leonard, E., Y. Yan, and M.A. Koffas. 2006. Functional expression of a P450 flavonoid hydroxylase for the biosynthesis of plantspecific hydroxylated flavonols in Escherichia coli. Metab. Eng. 8:172-181. DOI ScienceOn |
7 | Li, F., Z. Jin, D. Zhao, C. Fu, and F. Ma. 2006. Overexpression of the Saussurea medusa chalcone isomerase gene in S. involucrate hairy root cultures enhances their biosynthesis of apigenin. Phytochemistry 67:553-560 DOI ScienceOn |
8 | Li, F., Z. Jin, W. Qu, D. Zhao, and F. Ma. 2006. Cloning of a cDNA encoding the Saussurea medusa chalcone isomerase and its expression in transgenic tobacco. Plant Physiol. Biochem. 44:455-461. DOI ScienceOn |
9 | Li, X., M. Gao, H. Pan, D. Cui, and M. Gruber. 2010. Purple canola: arabidopsis PAP1 increases antioxidants and phenolics in Brassica napus leaves. J. Agric. Food Chem. 58:1639-1645. DOI ScienceOn |
10 | Manach, C., G. Williamson, C. Morand, A. Scalbert, and C. Remesy. 2005. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Amer. J. Clin. Nutr. 81:230-242. DOI |
11 | Muir, S.R., G.J. Collins, S. Robinson, S. Hughes, A. Bovy, C.H. Ric De Vos, A.J. van Tunen, and M.E. Verhoeyen. 2001. Overexpression of petunia chalcone isomerase in tomato results in fruit containing increased levels of flavonols. Nature Biotech. 19:470-474. DOI ScienceOn |
12 | Nishihara, M., T. Nakatsuka, and S. Yamamura. 2005. Flavonoid components and flower color change in transgenic tobacco plants by suppression of chalcone isomerase gene. FEBS Lett. 579:6074-6078. DOI ScienceOn |
13 | Park, J.S., J.B. Kim, K.J. Cho, C.I. Cheon, M.K. Sung, M.G. Choung, and K.H. Roh. 2008. Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa). Plant Cell Rep. 27:985-994. DOI ScienceOn |
14 | Fofana, B., D.J. McNally, C. Labbe, R. Boulanger, N. Benhamou, A. Seguin, and R.R. Belanger. 2002. Milsana-induced resistance in powdery mildew-infected cucumber plants correlates with the induction of chalcone synthase and chalcone isomerase. Mol. Plant Pathol. 61:121-132. DOI |
15 | Crozier, A., M.E.J. Lean, M.S. McDonald, and C. Black. 1997. Quantitative analysis of the flavonoid content of commercial tomatoes, onions, lettuce, and celery. J. Agric. Food Chem. 45:590-595. DOI ScienceOn |
16 | De Vries, I.M. 1997. Origin and domestication of Lactuca sativa L. Genet. Resour. Crop Evol. 44:165-174. DOI ScienceOn |
17 | DuPont, M.S., Z. Mondin, G. Williamson, and K.R. Price. 2000. Effect of variety, processing, and storage on the flavonoid glycoside content and composition of lettuce and endive. J. Agric. Food Chem. 48:3957-3964. DOI ScienceOn |
18 | Fuse, T., T. Sasaki, and M. Yano. 2001. Ti-Plasmid vectors useful for functional analysis of rice genes. Plant Biotechnol. 18:219-222. DOI ScienceOn |
19 | Hollman, P.C. and M.B. Katan. 1999. Dietary flavonoids: Intake, health effects and bioavailability. Food Chem. Toxicol. 37: 937-942. DOI ScienceOn |
20 | Jang, S.W., E.H. Lee, and W.B. Kim. 2007. Analysis of research and development of lettuce in Korea. Kor. J. Hort. Sci. Technol. 25:295-303 |
21 | Kim, S.R., J. Lee, S.H. Jun, S. Park, H.G. Kang, S. Kwon, and G. An. 2003.Transgene structures in T-DNA-inserted rice plants. Plant Mol. Biol. 52:761-773. DOI ScienceOn |
22 | Kim, S., R. Jones, K.S. Yoo, and L.M. Pike. 2004. Gold color in onions (Allium cepa): A natural mutation of the chalcone isomerase gene resulting in a premature stop codon. Mol. Genet. Genomics 272:411-419. DOI ScienceOn |
23 | Kodan, A., H. Kuroda, and F. Sakai. 2002. A stilbene synthase from Japanese red pine (Pinus densiflora): Implications for phytoalexin accumulation and down-regulation of flavonoid biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 99:3335-3339. DOI ScienceOn |
24 | Borevitz, J.O., Y. Xia, J. Blount, R.A. Dixon, and C. Lamb. 2000. Activation tagging identifies a conserved MYB regulator of phenylpropanoid biosynthesis. Plant Cell. 12:2383-2394. DOI |
25 | Avramova, Z.V. 2002. Heterochromatin in animals and plants. Similarities and differences. Plant Physiol. 129:40-49. DOI ScienceOn |