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http://dx.doi.org/10.5656/KSAE.2017.03.0.008

Insect Pest Control Technique Using dsRNA  

Kim, Yonggyun (Department of Plant Medicals, Andong National University)
Publication Information
Korean journal of applied entomology / v.56, no.2, 2017 , pp. 153-164 More about this Journal
Abstract
Gene silencing using double-stranded RNA (dsRNA) has been widely used in functional genomics in biological organisms. Its principle stems from RNA interference (RNAi), a post-transcriptional control of gene expression. Suppression of specific gene expression using dsRNA may give significant lethal effect. Insect pest control exploits this molecular process to develop novel insecticides using specific dsRNAs. This review explains core principles of RNAi using dsRNA. Then it illustrates various examples to control insect pests using dsRNAs. It also discusses limitations to control insect pests using dsRNAs. Finally, it provides several breakthroughs to develop dsRNA insecticides.
Keywords
RNA interference; dsRNA; Insect pest; Control; Insecticide;
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