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http://dx.doi.org/10.6114/jkood.2015.28.3.101

Clinical Study of Twenty-seven Case of Treating Acne scar Using Microneedle Therapy and Subcision Combined with Beevenom Pharmacopuncture Therapy  

Kim, Hye-Yoon (Jeonju Pibro Korean Medicine Clinic)
Hong, Seok-Hoon (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Won-kwang University)
Park, In-Hae (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Won-kwang University)
Heo, Eun-Sun (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Won-kwang University)
Noh, Hyeon-Min (Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine, College of Korean Medicine, Won-kwang University)
Shin, Sun-Ho (Department of Internal Medicine of Korean Medicine, College of Korean Medicine, Won-kwang University)
Publication Information
The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology / v.28, no.3, 2015 , pp. 101-113 More about this Journal
Abstract
Objectives : Microneedle therapy and Subcision are commonly used for therapeutic modalities of acne scars in Korean medicine. Beevenom could promote the expression of various cytokines, enzymes and receptors related to increasing collagen content of connective tissues. Through this mechanism, we considered that Beevenom pharmacopuncture therapy is applicable to the treatment of acne scars. We investigated twenty-seven patients with acne scars treated by Microneedle therapy and Subcision combined with Beevenom pharmacopuncture therapy and evaluated the clinical effect.Methods : Twenty-seven patients with acne scars were treated by Microneedle therapy and Subcision combined with Beevenom pharmacopuncture therapy and evaluated the clinical effect. for twelve weeks. The severity of acne scars and treatment effect were evaluate by standardized photography, GASC, ECCA scale and patient`s satisfaction. And side effects was also checked.Results : After twelve weeks for treatment, there was an improvement in GASC, ECCA scale. 77.8% of patient replied excellent or good on patient satisfaction survey. One patient sufferied from pruritus, papules and comedones as side effect of treatment.Conclusion : It can be considered that Microneedle, Subcision, Beevenom pharmacopuncture combining therapy are effective method for treating acne scars.
Keywords
Acne scars; Microneedle therapy; Subcision; Beevenom Pharmacopuncture;
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Times Cited By KSCI : 3  (Citation Analysis)
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1 An JC, Kwon KR, Lee EH, Cha BC. A Comparative Study on the Antibacterial Activity and Antioxidant Effect of Between the Bee Venom and Sweet Bee Venom. J of Korean Institute of Herbal-Acupuncture. 2006;9(3):97-104.
2 Ko HY, Lee YH, Lee HS. The Effects of Placental Extract Using Microneedle Therapy System on Acne Scars. Korean J of Aesthetics and Cosmetology. 2009;7(4):15-22.
3 Lee JR, Na SY, Sohn YM, Noh JY. Microneedle Therapy and TCA CROSS Combination Treatment for Deep Acne Scar. Korean J Dermatol. 2008;46(2s):157-8.
4 Lee WR, Park JH, Kim KH, An HJ, Han SM, Park KK. Effects of Bee Venom on Propionibacterium acnes-induced inflammatory Skin Disease in Mice. Korean J of Pharmacognosy. 2011;42(4):366-70.
5 Han SM, Kim JM, Lee KG, Park KK, Chang YC. Inhibitory Effects of Purified Bee Venom on Melanin Synthesis. J of the Pharmaceutical Society of Korea. 2012;56(4):254-9.
6 Kim JM, Kim YB. The Effect of Bee Venom Therapy on Skin Aging. J of Korean Med Ophthalmology Otolaryngology Dermatol. 2010;23(2):27-40.
7 Han SM, Lee KG, Yeo JH, Kim WT, Park KK. Antimicrobial Property of honeybee(Apis mellifera L.) venom against Propionibacteruim acnes and Aerobic Skin Flora. Korean J of Pharmacognosy. 2009;40(3):173-7.
8 Han SM, Hong IP, Woo SO, Chun SN, Han CS. The Effect of Cosmetic Included Purified Bee Venom on the Improvement of Skin Wrinkle. J of the Korean Society of Cosmetology. 2015;21(2):288-92.
9 Seo JC, Leem KH, Han SW. Antioxidant Effect of Bee Venom Herbal Acupuncture. J of Korean Institutue of Herbal-Acupuncture. 2003;6(1):67-72.
10 Lee WR, Park JH, Kim KH, An HJ, Han SM, Park KK. Effects of Bee Venom on Propionibacterium acnes-induced inflammatory Skin Disease in Mice. Korean J of Pharmacognosy. 2011;42(4):366-70.
11 Han SM, Han CS. The effect of cosmetic included purified bee venom on the improvement of acne. J of the Korean Society of Cosmetology. 2012;18(2):391-6.   DOI
12 Kim HI, Kim CM, Shin HJ, Lee CH. Experimental Study on the Expression of Hair Growth Related Factors after Bee Venom Acupuncture Therapy. Korean J. Oriental Physiology&Pathology. 2011;25(3):496-502.
13 Jung HJ, Park KK, Park JH, Kim KH, Cho CH, Choe JY, et al. Effects of Whole Bee Venom on Expression of TNF-α, Nitric Oxide, TGF-β1 in Collagen-induced Arthritis Model. Korean J. Apiculture. 2007;22(2):181-8.
14 Lee JD. Bee-Venom Theraphy-Method of Clinical Approach. J of Oriental Medicine. 2000;21(3):3-8.
15 Greg JG, Jennifer AB, Postacne scarring – a quantitative global scarring grading system. J Cosmetic Dermatol. 2006;5;48-52.   DOI   ScienceOn
16 Dreno B, Khammari A, Orain N, Noray C, Meria-kieny C, Mery S, et al. ECCA grading scale: an original validated acne scar grading scale for clinical practice in dermatology. Dermatology. 2007;214;46-51.   DOI   ScienceOn
17 Carolyn IJ, Jeffrey SD, FRCPC, Michael SK. Acne scarring:A classification system and review of treatment options. J Am Acad Dermatol. 2001;45(1);113.
18 Thiboutot D, Gollnick H, Bettoli V, Dreno B, Kang S, Leyden JJ, et al. New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group. J Am Acad Dermatol 2009;60:21-50.   DOI
19 Alami HS, Balighi K, Lajevardi V, Akbari E. Subcision suction method:a new successful combination therapy in treatment of atrophic acne scars and other depressed scars. J Eur Acad Dermatol Venereaol. 2011;25(1):92-9.   DOI
20 Orientreich DS, Orentreich N. Subcutaneous incisionless(subcision) surgery for the correction of derpessed scars and wrinkles. Dermatol Surg. 1995;2:543-9.
21 Yekhae HwangJenaegyeong(YeongChu). Seoul: Yeogang Publisher. 2000:518.
22 Korean Dermatological Association. Dermatology. 5th. Seoul:RMGP. 2008:446-7.
23 Chae WS, Sug HS, Choi YS. A Comparative Study of the Efficacy and Safety of 100% TCA CROSS and Phenol CROSS for Atrophic Acne Scarring. Korean J Dermatol. 2014;52(5):293-301.
24 Tosti A, Padova MD, Beer K. Acne Scar-Classification and treatment. Seoul:Gabon Medical Book, Inc. 2010:1-2, 21, 59-61.
25 Hwang KK. Treatment of Acne scar. Korean J Dermatol. 40(2s):29-31.
26 Baek SC, Hong MS, Jegal H, Jin YH, Joo TM, Lee SJ, et al. A Clinical Report on The Atrophic Acne Scar with Subcision. J Korean Med Ophthalmol Otolaryngol Dermatol. 2012;25(4):80-8.   DOI   ScienceOn
27 Heo JE, Yun JM, Shin SH. Case Study of Treating Acne Scars Using Reconstruction of Skin Scars and Auto Microneedle Therapy System. J Korean Med Ophthalmol Otolaryngol Dermatol. 2013;26(4):127-34.   DOI   ScienceOn
28 Jacob CI, Dover JS, Kaminer MS. Acne scarring:A classification system and review of treatment options. J Am Acad Dermatol. 2001;45:109-10.   DOI
29 Goodman GJ. Management of post-ance scarring:What are the options for treatment? Am J Clin Dermatol 2000;1:3.   DOI   ScienceOn
30 Kwon GR, Koh HK. The Clinical Observation of Immune Response by Korean Bee Venom Therapy. J of Korean Acupuncture & Moxibustion Medicine Society. 2000;17(1):169-74.
31 An HJ, Lee CK, Park JH, Kim KH, Lee WR, Park IY, et al. Effects of Bee Venom on Papain-induced Osteoarthritis in an Animal Model. Korean J of Pharmacognosy. 2012;43(2):167-72.
32 Lee KS, Kim YR, Choi HS. Vase Study of Treating Acne Scar Using Scar Regeneration Acupuncture Therapy and Micro-needle Therapy. J Kor Acupunc & Moxibus. 2012;29(4):81-91.