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http://dx.doi.org/10.12701/yujm.2019.00136

Endoscopic features aiding the diagnosis of gastric mucosa-associated lymphoid tissue lymphoma  

Park, Byung Sam (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine)
Lee, Si Hyung (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Yeungnam University College of Medicine)
Publication Information
Journal of Yeungnam Medical Science / v.36, no.2, 2019 , pp. 85-91 More about this Journal
Abstract
The incidence of gastric mucosa-associated lymphoid tissue (MALT) lymphoma is increasing worldwide, but the diagnosis is difficult. Most patients are asymptomatic or complain of nonspecific gastrointestinal symptoms. As the endoscopic features of gastric MALT lymphoma are variable and nonspecific, the possibility of this condition may be overlooked during esophagogastroduodenoscopy, and it remain undiagnosed. Therefore, this condition needs to be considered when an abnormal mucosa is observed during this procedure. Biopsy performed during endoscopy is the primary diagnostic test, but false negative results are possible; large numbers of samples should be collected from both normal and abnormal mucosae. Endoscopic ultrasonography is useful to assess the depth of invasion and to predict the treatment response. After treatment, follow-up tests are required every 3 months until complete remission is achieved, and annually thereafter. Early diagnosis of gastric MALT lymphoma is difficult, and its diagnosis and follow-up require wide experience and competent endoscopic technique.
Keywords
Diagnosis; Follow-up studies; Gastrointestinal endoscopy; Marginal zone B-cell lymphoma; Stomach neoplasms;
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