Optimized TOF-PET detector using scintillation crystal array for brain imaging |
Leem, Hyuntae
(Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University)
Choi, Yong (Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University) Jung, Jiwoong (Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University) Park, Kuntai (Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University) Kim, Yeonkyeong (Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University) Jung, Jin Ho (Molecular Imaging Research & Education (MiRe) Laboratory, Department of Electronic Engineering, Sogang University) |
1 | S. Vandenberghe, E. Mikhaylova, E. D'Hoe, P. Mollet, J.S. Karp, Recent developments in time-of-flight PET, Eur. J. Nucl. Med. Mol. Imag. Phys. 3 (2016). https://ejnmmiphys.springeropen.com/articles/10.1186/s40658-016-0138-3. |
2 | S.W. Lee, Y. Cho, J. Kang, J.H. Jung, Development of a multiplexed readout with high position resolution for positron emission tomography, Nucl. Instrum. Methods Phys. Res. A 850 (2017) 42-47. DOI |
3 | M. Conti, B. Bendriem, The new opportunities for high time resolution clinical TOF PET, Clin. Transl. Imaging 7 (2019), https://doi.org/10.1007/s40336-019-00316-5. DOI |
4 | S. Gundacker, F. Acerbi, E. Auffray, A. Ferri, A. Gola, M.V. Nemallapudi, G. Paternoster, C. Piemonte, P. Lecoq, State of the art timing in TOF-PET detectors with LuAG, GAGG and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs, J. Instrum. 11 (2016). https://iopscience.iop.org/article/10.1088/1748-0221/11/08/P08008. |
5 | E. Roncali, M.A.M. Shirazi, A. Badano, Modelling the transport of optical photons in scintillation detectors for diagnostic and radiotherapy imaging, Phys. Med. Biol. 62 (2017) R207-R235. DOI |
6 | E. Roncali, M. Stockhoff, S.R. Cherry, An integrated model of scintillator-reflector properties for advanced simulations of optical transport, Phys. Med. Biol. 62 (2017) 4811-4830. DOI |
7 | D.J.V. Elburg, S.D. Noble, S. Hagey, A. Goertzen, Comparison of acrylic polymer adhesive tapes and silicone optical grease in light sharing detectors for positron emission tomography, Phys. Med. Biol. 63 (2018). https://iopscience.iop.org/article/10.1088/1361-6560/aaa815. |
8 | E. Lorincz, G. Erdei, I. Peczeli, C. Steinbach, F. Ujhelyi, T. Bukki, Modeling and optimization of scintillator arrays for PET detectors, IEEE Trans. Nucl. Sci. 57 (2010) 48-54. DOI |
9 | T. Nagano, N. Hosokawa, A. Ishida, R. Tsuchiya, K. Sato, K. Yamamoto, Timing Resolution Dependence on MPPC Geometry and Performance, 2013. IEEE Nucl. Sci. Symp. Med. Imag. Conf., Seoul, Korea (South), 27 Oct.-2 Nov. |
10 | K.B. Kim, Y. Choi, J.W. Jung, S.W. Lee, H.-J. Choe, H.T. Leem, Analog and digital signal processing method using multi-time-over-threshold and FPGA for PET, Med. Phys. 45 (2018) 4104-4111. DOI |
11 | C.-Y. Liu, A.L. Goertzen, Improved event positioning in a gamma ray detector using an iterative position-weighted centre-of-gravity algorithm, Phys. Med. Biol. 58 (2013) N189-N200. DOI |
12 | H.T. Leem, Y. Choi, K.B. Kim, S. Lee, S. Yamamoto, J.-Y. Yeom, Performance evaluation of a sub-millimeter spatial resolution PET detector module using a digital silicon photomultiplier coupled LGSO array, Nucl. Instrum. Methods Phys. Res. A 846 (2017) 18-22. DOI |
13 | H.-J. Choe, Y. Choi, W. Hu, J. Yan, J.H. Jung, Development of capacitive multiplexing circuit for SiPM-based time-of-flight (TOF) PET detector, Phys. Med. Biol. 62 (2017) N120-N133. DOI |
14 | K.J. Hong, Y. Choi, J.H. Jung, J. Kang, W. Hu, H.K. Lim, Y. Huh, S. Kim, J.W. Jung, K.B. Kim, M.S. Song, H.-W. Park, A prototype MR insertable brain PET using tileable GAPD arrays, Med. Phys. 40 (2013) 1-12. DOI |
15 | J.H. Jung, Y. Choi, J. Jung, S. Kim, H.K. Lim, K.C. Im, C.H. Oh, H. Park, K.M. Kim, J.G. Kim, Development of PET/MRI with insertable PET for simultaneous PET and MR imaging of human brain, Med. Phys. 42 (2015) 2354-2363. DOI |
16 | H. Shin, Y. Choi, Y. Huh, J.H. Jung, T.S. Suh, Conceptual study of brain dedicated PET improving sensitivity, Kor. Soc. Med. Phys. 27 (2016) 236-240. |
17 | C. Catana, Development of dedicated brain PET imaging devices: recent advances and future perspectives, J. Nucl. Med. 60 (2019) 1044-1052. DOI |
18 | C. Kim, M. Ito, D.L. McDaniel, Effect of Scintillation Crystal Surface Finish in the Light Sharing TOF PET Detector, 2016. IEEE Nucl. Sci. Symp. Conf. Rec, IEEE NSS/MIC/RTSD, Strausbourg, France, 29 Oct.-6 Nov. |
19 | E. Berg, E. Roncali, S.R. Cherry, Optimizing light transport in scintillation crystals for time-of-flight PET: an experimental and optical Monte Carlo simulation study, Biomed. Opt Express 6 (2015) 2220-2230. DOI |
20 | K. Wienhard, M. Schmand, M.E. Casey, K. Baker, J. Bao, L. Eriksson, W.F. Jones, C. Knoess, M. Lenox, M. Lercher, P. Luk, C. Michel, J.H. Reed, N. Richerzhagen, J. Treffert, S. Vollmar, J.W. Young, W.D. Heiss, R. Nutt, The ECAT HRRT: performance and first clinical application of the new high resolution research tomograph, IEEE Trans. Nucl. Sci. 49 (2002) 104-110. DOI |
21 | C.M. Lavelle, W. Shanks, C. Chiang, M. Nichols, J. Osborne Jr., A. Herschelman, B. Brown, M. Cho, Approaches for single channel large area silicon photomultiplier array readout, AIP Adv. 9 (2019), https://doi.org/10.1063/1.5088503. DOI |
22 | M. Conti, Focus on time-of-flight PET: the benefits of improved time resolution, Eur. J. Nucl. Med. Mol. Imag. Phys. 38 (2011) 1147-1157. DOI |
23 | S. Majewski, J. Proffitt, J. Brefczynski-Lewis, A. Stolin, A.G. Weisenberger, W. Xi, R. Wojcik, HelmetPET: A Silicon Photomultiplier Based Wearable Brain Imager, in: IEEE Nucl. Sci. Symp. Conf. Rec, IEEE NSS/MIC/RTSD, Valencia, Spain, Oct. 2011, pp. 23-29. |
24 | J.S. Karp, S. Surti, M.t E.D. Witherspoon, G. Muehllehner, Benefit of time-of-flight in PET: experimental and clinical results, J. Nucl. Med. 48 (2008) 462-470. |
25 | H. Thoen, V. Keereman, P. Mollet, R. Van Holen, S. Vandenberghe, Influence of detector pixel size, TOF resolution and DOI on image quality in MR-compatible whole-body PET, Phys. Med. Biol. 58 (2013) 6459-6479. DOI |
26 | E. Yoshida, H. Tashima, G. Akamatsu, Y. Iwao, M. Takahashi, T. Yamashita, T. Yamaya, 245 ps-TOF brain-dedicated PET prototype with a hemispherical detector arrangement, Phys. Med. Biol. 65 (2020). https://iopscience.iop.org/article/10.1088/1361-6560/ab8c91. |
27 | N.Y. Lee, Y. Choi, Simulation studies on depth of interaction effect correction using a Monte Carlo computed system matrix for brain positron emission tomography, Comput. Methods Progr. Biomed. 108 (2012), https://doi.org/10.1016/j.cmpb.2012.05.007. DOI |
28 | V. Nadig, D. Schug, B. Weissler, V. Schulz, Evaluation of the PETsys TOFPET2 ASIC in multi-channel coincidence experiments, Eur. J. Nucl. Med. Mol. Imag. Phys. 30 (2021). https://ejnmmiphys.springeropen.com/articles/10.1186/s40658-021-00370-x. |
29 | C.R. Schmidtlein, J.N. Turner, M.O. Thompson, K.C. Mandal, I. Haggstrom, J. Zhang, J.L. Humm, D.H. Feiglin, A. Krole, Initial performance studies of a wearable brain positron emission tomography camera based on autonomous thin-film digital Geiger avalanche photodiode arrays, J. Med. Imag. 4 (2017), https://doi.org/10.1117/1.JMI.4.1.011003. DOI |
30 | M. Aykac, F. Bauer, C.W. Williams, M. Loope, M. Schmand, Timing performance of Hi-Rez detector for time-of-flight (TOF) PET, IEEE Trans. Nucl. Sci. 53 (2006) 1084-1089. DOI |