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http://dx.doi.org/10.12812/ksms.2013.15.4.427

Evaluation of 18F-FDG PET/CT Image Distortion by NEMA IEC Body Phantom  

Park, jooncheol (Dept. of Radiological Technology, Anshan University)
Yang, hanjoon (Dept. of International Radiological Sciences, Hallym University of Graduate Studies)
Publication Information
Journal of the Korea Safety Management & Science / v.15, no.4, 2013 , pp. 427-433 More about this Journal
Abstract
Recently, 18F-FDG PET based CT scan was a critical examination that the after, before plan diagnosis and treatment of tumors. But, due to the distortion of SUV that should be proportional to the metabolic rate of glucose in the tumor, the other measurement methods are being on study. In this study, compared the degree of distortion of SUV that according to the volume of the tumor analysis ROI and VOI using the NEMA IEC Phantom. The results, the SUVmax, mean value are rapidly decreased with threshold value 500 mm2 interval of the ROI analysis, 1500 mm3 interval of the VOI analysis. When compared SUVmax value SUVmean, ROI and VOI analysis VOI measurements was 1.077 times higher SUVmax was 0.981 times highe compared to the value of the ROI measurement. Compare MTV, SUV 2.0 as measured by the volume of the VOI to Volume showed a slightly higher results(Volume / MTV = $93.4 %{\pm}14.8 %$). Considering the above results, Tumor evaluation by 18F-FDG PET / CT scan Consider each threshold value should be analyzed due to larger SUV's Distortion depending on the size of the tumor. VOI analysis is recommended. because it showed the VOI analysis is higher than the ROI analysis SUVmax and lower SUVmean due to VOI analysis than once as a measure of the wider area as measured ROI analysis. MTV (R2 = 0.999), a result close to the actual size of the tumor. but, more research is needed in this regard, because SUV according to the standards of value are affected.
Keywords
18F-FDG PET/CT; NEMA IEC Phantom; SUVmax; SUVmean; MTV;
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