[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5808/GI.2018.16.4.e21

An Advanced Understanding of Uterine Microbial Ecology Associated with Metritis in Dairy Cows

Jeon, Soo Jin (Department of Biomedical Veterinary Sciences, College of Veterinary Medicine, Long Island University)
Galvao, Klibs N. (Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida)

Publication Information

Abstract

Metritis, the inflammation of the uterus caused by polymicrobial infections, is a prevalent and costly disease to the dairy industry as it decreases milk yield, survival, and the welfare of dairy cows. Although affected cows are treated with broad-spectrum antibiotics such as ceftiofur, endometrial and ovarian function are not fully recovered, which results in subfertility and infertility. According to culture-dependent studies, uterine pathogens include Escherichia coli, Trueperella pyogenes, Fusobacterium necrophorum, and Prevotella melaninogenica. Recent studies using high-throughput sequencing observed very low relative abundance of Escherichia coli, Trueperella pyogenes, and Prevotella melaninogenica in cows with metritis. Herein, we propose that metritis is associated with a dysbiosis of the uterine microbiota, which is characterized by high abundance of Bacteroides, Porphyromonas, and Fusobacterium.

Keywords

cattle; metagenomics; microbiota; uterine diseases;

Citations & Related Records

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