Structural Analysis of Recombinant Human Preproinsulins by Structure Prediction, Molecular Dynamics, and Protein-Protein Docking |
Jung, Sung Hun
(Department of Biological Science, Sangji University)
Kim, Chang-Kyu (WeGreen, Inc.) Lee, Gunhee (Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea) Yoon, Jonghwan (Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea) Lee, Minho (Catholic Precision Medicine Research Center, College of Medicine, The Catholic University of Korea) |
1 | Shi Y, Hu FB. The global implications of diabetes and cancer. Lancet 2014;383:1947-1948. DOI |
2 | Wright JR Jr, Yang H, Hyrtsenko O, Xu BY, Yu W, Pohajdak B. A review of piscine islet xenotransplantation using wild-type tilapia donors and the production of transgenic tilapia expressing a "humanized" tilapia insulin. Xenotransplantation 2014;21:485-495. DOI |
3 | Koolman J, Roehm KH. Color Atlas of Biochemistry. 2nd ed. Stuttgart: Thieme, 2005. |
4 | Mohsin F, Craig ME, Cusumano J, Chan AK, Hing S, Lee JW, et al. Discordant trends in microvascular complications in adolescents with type 1 diabetes from 1990 to 2002. Diabetes Care 2005;28:1974-1980. DOI |
5 | Chistiakov DA, Tyurina I. Current strategies and perspectives in insulin gene therapy for diabetes. Expert Rev Endocrinol Metab 2007;2:27-34. DOI |
6 | Castellanos-Serra LR, Hardy E, Ubieta R, Vispo NS, Fernandez C, Besada V, et al. Expression and folding of an interleukin-2-proinsulin fusion protein and its conversion into insulin by a single step enzymatic removal of the C-peptide and the N-terminal fused sequence. FEBS Lett 1996;378:171-176. DOI |
7 | Min CK, Son YJ, Kim CK, Park SJ, Lee JW. Increased expression, folding and enzyme reaction rate of recombinant human insulin by selecting appropriate leader peptide. J Biotechnol 2011;151:350-356. DOI |
8 | Malik A, Jenzsch M, Lubbert A, Rudolph R, Sohling B. Periplasmic production of native human proinsulin as a fusion to E. coli ecotin. Protein Expr Purif 2007;55:100-111. DOI |
9 | Chen JQ, Zhang HT, Hu MH, Tang JG. Production of human insulin in an E. coli system with Met-Lys-human proinsulin as the expressed precursor. Appl Biochem Biotechnol 1995;55:5-15. DOI |
10 | Nilsson J, Jonasson P, Samuelsson E, Stahl S, Uhlen M. Integrated production of human insulin and its C-peptide. J Biotechnol 1996;48:241-250. DOI |
11 | Roy A, Kucukural A, Zhang Y. I-TASSER: a unified platform for automated protein structure and function prediction. Nat Protoc 2010;5:725-738. DOI |
12 | Winter J, Lilie H, Rudolph R. Renaturation of human proinsulin: a study on refolding and conversion to insulin. Anal Biochem 2002;310:148-155. DOI |
13 | Yang Y, Hua QX, Liu J, Shimizu EH, Choquette MH, Mackin RB, et al. Solution structure of proinsulin: connecting domain flexibility and prohormone processing. J Biol Chem 2010;285: 7847-7851. DOI |
14 | Baker EN, Blundell TL, Cutfield JF, Cutfield SM, Dodson EJ, Dodson GG, et al. The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos Trans R Soc Lond B Biol Sci 1988;319:369-456. DOI |
15 | Hornak V, Abel R, Okur A, Strockbine B, Roitberg A, Simmerling C. Comparison of multiple Amber force fields and development of improved protein backbone parameters. Proteins 2006;65:712-725. DOI |
16 | Zhang C, Mortuza SM, He B, Wang Y, Zhang Y. Templatebased and free modeling of I-TASSER and QUARK pipelines using predicted contact maps in CASP12. Proteins 2017 Oct 30 [Epub]. https://doi.org/10.1002/prot.25414. DOI |
17 | Yang J, Zhang W, He B, Walker SE, Zhang H, Govindarajoo B, et al. Template-based protein structure prediction in CASP11 and retrospect of I-TASSER in the last decade. Proteins 2016;84 Suppl 1:233-246. DOI |
18 | Abraham MJ, Murtola T, Schulz R, Pall S, Smith JC, Hess B, et al. GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers. SoftwareX 2015;1:19-25. |
19 | Yu J, Vavrusa M, Andreani J, Rey J, Tuffery P, Guerois R. InterEvDock: a docking server to predict the structure of protein-protein interactions using evolutionary information. Nucleic Acids Res 2016;44:W542-W549. DOI |
20 | Garzon JI, Lopez-Blanco JR, Pons C, Kovacs J, Abagyan R, Fernandez-Recio J, et al. FRODOCK: a new approach for fast rotational protein-protein docking. Bioinformatics 2009;25:2544-2551. DOI |
21 | Dong GQ, Fan H, Schneidman-Duhovny D, Webb B, Sali A. Optimized atomic statistical potentials: assessment of protein interfaces and loops. Bioinformatics 2013;29:3158-3166. DOI |