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http://dx.doi.org/10.5808/GI.2014.12.2.76

SFannotation: A Simple and Fast Protein Function Annotation System  

Yu, Dong Su (Korean BioInformation Center (KOBIC), Korea Research Institute of Bioscience and Biotechnology (KRIBB))
Kim, Byung Kwon (BioNano Health Guard Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB))
Publication Information
Genomics & Informatics / v.12, no.2, 2014 , pp. 76-78 More about this Journal
Abstract
Owing to the generation of vast amounts of sequencing data by using cost-effective, high-throughput sequencing technologies with improved computational approaches, many putative proteins have been discovered after assembly and structural annotation. Putative proteins are typically annotated using a functional annotation system that uses extant databases, but the expansive size of these databases often causes a bottleneck for rapid functional annotation. We developed SFannotation, a simple and fast functional annotation system that rapidly annotates putative proteins against four extant databases, Swiss-Prot, TIGRFAMs, Pfam, and the non-redundant sequence database, by using a best-hit approach with BLASTP and HMMSEARCH.
Keywords
bioinformatics; gene product; protein annotation;
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