[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5808/GI.2009.7.3.178

COCAW: A Genome-wide Pattern Search System for Designing Microbial Probes

Ryu, Seung-Hee (Visual and Biomedical Computing Lab., Pusan National University)
Park, Kie-Jung (PNU SuperComputing Center, Pusan National University)
Lee, Do-Hoon (Visual and Biomedical Computing Lab., Pusan National University)
Kim, Cheol-Min (School of Medicine, Pusan National University)

Publication Information

Abstract

A few bioinformatics tools have been used to find out conserved regions as probes. We have developed a system based on a heuristic method with web interfaces to find out conserved regions against microbial genomes. The system runs in real time by using relative entropy in limited narrow regions and detecting similar regions between pair regions with local alignment. The system could be useful to find out conserved regions as genome-wide scale.

Keywords

genome project; genome-wide search; primer design; probe design;

Citations & Related Records

Reference

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