[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5808/GI.2008.6.1.054

GTVseq: A Web-based Genotyping Tool for Viral Sequences

Shin, Jae-Min (SBscience Inc.)
Park, Ho-Eun (SBscience Inc.)
Ahn, Yong-Ju (Department of Bioinformatics, Soongsil University)
Cho, Doo-Ho (SBscience Inc.)
Kim, Ji-Han (Department of Bioinformatics, Soongsil University)
Kee, Mee-Kyung (Department of Bioinformatics, Soongsil University)
Kim, Sung-Soon (Department of Immunology and Pathology, National Institute of Health)
Lee, Joo-Shil (Department of Immunology and Pathology, National Institute of Health)
Kim, Sang-Soo (Department of Bioinformatics, Soongsil University)

Publication Information

Abstract

Genotyping Tool for Viral SEQuences (GTVseq) provides scientists with the genotype information on the viral genome sequences including HIV-1, HIV-2, HBV, HCV, HTLV-1, HTLV-2, poliovirus, enterovirus, flavivirus, Hantavirus, and rotavirus. GTVseq produces alternative and additive genotype information for the query viral sequences based on two different, but related, scoring methods. The genotype information produced is reported in a graphical manner for the reference genotype matches and each graphical output is linked to the detailed sequence alignments between the query and the matched reference sequences. GTVseq also reports the potential 'repeats' and/or 'recombination' sequence region in a separated window. GTVseq does not replace completely other well-known genotyping tools such as NCBI's virus sequence genotyping tool (http://www.ncbi. nlm.nih.gov/projects/genotyping/formpage.cgi), but provides additional information useful in the confirmation or for further investigation of the genotype(s) for the newly isolated viral sequences.

Keywords

Genotyping; Recombination; Subtyping; Viral Genome; Viral Sequence; Virus database; Visualization; Web-Server Introductio;

Citations & Related Records

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