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New Approach to the Analysis of Palindromic Structure in Genome Sequences  

Kim, Seok-Won (Genome Research Center, KRIBB)
Lee, Yong-Seok (Department of Parasitology and Malariology, PICR, College of Medicine and Frontier Inje Research for Science and Technology, Inje University)
Choi, Sang-Haeng (Genome Research Center, KRIBB)
Chae, Sung-Hwa (Genome Research Center, KRIBB)
Kim, Dae-Won (Genome Research Center, KRIBB)
Park, Hong-Seog (Genome Research Center, KRIBB)
Abstract
PABAP (Palindrome Analysis by BLAST Program) is an analysis system that identifies palindromic sequences from a large genome sequence up to several megabases long. It uses NCBI BLAST as a searching engine, and data processing such as alignment filtration and detection of inverted repeats which satisfy user-defined parameters is performed by manipulating data after populating into a MySQL database. PABAP outperforms publicly available palindrome search program in that it can detect large palindrome with internal spacer at a faster speed from bacterial genomes. It is a standalone application and is freely available for noncommercial users.
Keywords
palindrome; inverted repeat; BLAST;
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