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http://dx.doi.org/10.15207/JKCS.2020.11.1.077

A convergence study on the Positive Rate of Hepatitis B Surface Antibody by Age before and after HBV Vaccination  

Kim, Jiro (Department of Clinical Laboratory Science, Cheju Halla University)
Lee, Kyu-taeg (Department of Laboratory Medicine, Cheju Halla General Hospital)
Chong, Moo-Sang (Department of Clinical Laboratory Science, Cheju Halla University)
Publication Information
Journal of the Korea Convergence Society / v.11, no.1, 2020 , pp. 77-82 More about this Journal
Abstract
In order to analyze the positive rate of hepatitis B surface antibody by age before and after hepatitis B vaccination, 13,855 serum specimens who were referred for the hepatitis B surface antibody test at the General Hospital of Jeju Hospital were examined by CMIA method. The positive rate of HBs Ab was 5,176 (37.36%). The positive rate according to gender was 40.13% for female and 34.77% for male. The age group with the highest HBs Ab average was in their 40's (399.86 mIU/mL), while the lowest age group was in the 90's (211.50 mIU/mL). It is remarkable that the age group with the highest HBs Ab positive rate is in the 30's, and that teenagers (age group of 10-20 years) had the lowest positive rate. Especially 15, 18, 19 years old was statistically significant. Consideration should be given to determining the titer of vaccination and to clarify the timing of vaccination.
Keywords
Convergence; HBs Antibody; Hepatitis B vaccination; Hepatitis B virus;
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1 M. K. Jang, J. Y. Lee, J. H. Lee, Y. B. Kim, H. Y. Kim & J. Y. Yoo. (2000). The investigation for the change of HBs Ag positive rate of grade.junior high.high-schoolers for recent 3 years in Kang won province. Korean J Med, 58(6), 608-615.
2 D. J. West & G. B. Calandra. (1996). Vaccine induced immunologic memory for hepatitis B surface antigen: implications for policy on booster vaccination. Vaccine, 14(11), 1019-1027. DOI : 10.1016/0264-410x(96)00062-x   DOI
3 W. K. Lee. (2003). Characteristics of Hepatitis B Virus(HBV) and HBV DNA Quantitative Tests. Korean J Clin Microbiol, 6(2), 89-96.
4 H. M. Koh & J. S. Son. (2015). Seroprevalence of Hepatitis A and B Virus Antibody of Employees among Three Companies with Different Health Policy. J Korean Soc Occup Environ Hyg, 25(2), 229-235. DOI : 10.15269/jksoeh.2015.25.2.229   DOI
5 K. Kim & D. A. Kim. (2013). The Comparison between Serologic Tests and Magicplex HepaTrio Real-time PCR in the Diagnosis of Viral Hepatitis. Lab Med Online, 3(1), 23-28 DOI : 10.3343/lmo.2013.3.1.23   DOI
6 Y. J. Choi, K. S. Bae, K. H. Kim, D. K. Koh & J. H. Kim. (2018). Therapeutic Efficacy of Lamivudine in Children and Adolescents with Chronic Hepatitis B. Pediatr Infect Vaccine, 25(2), 72-81. DOI : 10.14776/piv.2018.25.e2   DOI
7 Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. (2015). Korea Health Statistics 2014: Korea National Health and Nutrition Examination Survey (KNHANES VI-2). Sejong: Ministry of Health and Welfare.
8 J. H. Kim, K. Seo & H. M. Kim. (2006). A comparative study for the outcome of perinatal hepatitis B prophylaxis according to the dosages of hepatitis B immunoglobulin. Seoul: Korea Centers for Disease Control and Prevention.
9 E. S. Jang. (2013). Diagnostic Tests for Viral Hepatitis. Korean J Med, 85(3), 267-271. DOI : 10.3904/kjm.2013.85.3.267   DOI
10 H. M. Kang et al. (2007). Recent etiology and clinical features of acute viral hepatitis in a single center of Korea. Korean J Hepatol, 13(4), 495-502. DOI : 10.3350/kjhep.2007.13.4.495   DOI
11 J. R. Kim. (1979). Study of hepatitis B vaccine. JKMA, 22, 1013-1025.
12 M. H. Lee. (2015). The Positive Rates of Anti-HBs and Titers of Antibody after Hepatitis B Vaccination. Korean J Clin Lab Sci, 47(2), 78-82. DOI : 10.15324/kjcls.2015.47.2.78   DOI
13 Y. K. Cho & B. C. Song. (2012). Prevention of Viral Hepatitis and Vaccination. Korean J Med, 82(2), 123-133. DOI : 10.3904/kjm.2012.82.2.123   DOI
14 H. B. Chae, J. H. Kim, J. K. Kim & H. J. Yim. (2009). Current status of liver diseases in Korea: hepatitis B. Korean J Hepatol, 15(Suppl 6), S13-S24. DOI : 10.3350/kjhep.2009.15.s6.s13   DOI
15 S. Jeong, H. W. Yim, S. H. Bae & W. C. Lee. (2008). Changes of hepatitis B surface antigen seroprevalence in Korea, 1998-2005. Korean J Epidemiol, 30(1), 119-127. DOI : 10.4178/kje.2008.30.1.119   DOI
16 W. Jilg, M. SChmit & F. Deinhard. (1988). Persistence of specifics antibodies after hepatitis B vaccination. J hepatology, 6(2), 201-207. DOI : 10.1016/s0168-8278(88)80032-1   DOI
17 I. T. Williams, S. T. Goldstein, J. Tufa, S. Tauilli, H. S. Margolis & F. J. Mahoney. (2003). Long term antibody response to hepatitis B vaccination beginning at birth and to subsequent booster vaccination. Pediatr Infect Dis J, 22(2), 157-163. DOI : 10.1097/01.inf.0000050463.28917.25   DOI
18 S. M. Song, W. I. Oh & D. W. Kim. (2002). Evaluation of Serologic Marker Tests for Hepatitis B Viral Infection Using the Automated Immunoassay System ARCHITECT i2000. Korean J Clin Pathol, 22(1), 42-46.
19 J. G. Sim, J. K. Seo, S. J. Suh. (1995). Prevalence and its changes of hepatitis B ciral markers from 1988 to 1993 in Korean children. J Korean Pediatr Soc, 38(11), 1535-1539.
20 S. J. Lee et al. (2001). A study on the change of HBsAg and Anti HBs positivies for a recent 15 year period in Korea. Korean J Hepatol, 7(3), 299-307.
21 M. H. Lee. (2015). The Positive Rates of Anti-HBs and Titers of Antibody after Hepatitis B Vaccination. Korean J Clin Lab Sci, 47(2), 78-82. DOI : 10.15324/kjcls.2015.47.2.78   DOI
22 A. Goudeau F. Dubois, G. Barin, MC. Dubois & P. Coursaget. (1983). Hepatitis B vaccine: Clinical trials high risk settings in France (September 1975-September 1982). Develop Biol Standard, 54, 267-278.
23 J. H. Na, H. M. Cho, K. T. Chung, S. Woo. Choi, M. J. Park & S. J. Sohn. (2006). Sero-Prevalence of Hepatitis B Virus in University Students. J Agri Med & Community Health, 31(3), 245-253.
24 J. H. Seo. (2003). Hepatitis B Surface Antigen and Antibody Positive Rates of Children and Adolescents in Jeju. Clinical and Molecular Hepatology, 9(4), 304-314.