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http://dx.doi.org/10.15207/JKCS.2018.9.3.165

Fusion Analytical Sensitivity of Rapid Influenza Antigen Limit of Detection Tests for Human Influenza virus  

Song, Chang-Sub (Department of Clinical Laboratory Science, Dongnam Health University)
Sung, Hyun-Ho (Department of Clinical Laboratory Science, Dongnam Health University)
Kim, Jung-Hyun (Department of Clinical Laboratory Science, Jinju Health University)
Kim, Dae-Eun (Department of Clinical Laboratory Science, Jinju Health University)
Park, Chang-Eun (Department of Biomedical Laboratory Science, Molecular Diagnostics Research Institute, Namseoul University)
Yoon, Joong-Soo (Department of Clinical Laboratory Science, Kyunhdong University)
Publication Information
Journal of the Korea Convergence Society / v.9, no.3, 2018 , pp. 165-171 More about this Journal
Abstract
In this study, to analyze the detection of limit for sensitivity of the influenza rapid antigen test kit, the positive detection of limits were analyzed by serial dilution of influenza virus A and B type for five influenza rapid antigen test kits in Korea. As a result of analysis, visual measurement of type A were up to 1:8192 for the Wellsbio product and up to 1:4096 for the II product, up to 1:512 for the I and III products, and only 1:128 for the IV product, and type B were positive for up to 1:8192 for the Wellsbio product, up to 1: 4096 for the II product and up to 1:1024 for the I, III and IV products. For instrument readings with the same specimen, both A and B types were found to be positive for up to 1:8192 for the Wellsbio product, up to 1: 4096 for the II product, and up to 1:2048 for the I product. The sensitivity of the rapid antigen test for influenza differs greatly depending on the sampling area of the patient, infection period, specimen volume, etc. Therefore, it is necessary to observe exactly the collection timing and method of the specimen. And it is necessary further study to improve the sensitivity for influenza rapid antigen test.
Keywords
Influenza; Rapid antigen; Limit of detection; Sensitivity; Fusion analysis;
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