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http://dx.doi.org/10.15207/JKCS.2018.9.12.137

A study of growth inhibition mechanism of vinegar drink on Candida albicans  

Kim, Ae-Ok (Department of Preventive &Public Health Dentistry, Chonnam National University School of Dentistry)
Choi, Choong-Ho (Department of Preventive &Public Health Dentistry, Chonnam National University School of Dentistry)
Hong, Suk-Jin (Department of Preventive &Public Health Dentistry, Chonnam National University School of Dentistry)
Publication Information
Journal of the Korea Convergence Society / v.9, no.12, 2018 , pp. 137-143 More about this Journal
Abstract
The purpose of this study was to investigate the antifungal inhibition mechanism of fruit vinegar drinks against Candida albicans. To evaluate the effect of vinegar drinks on the growth and morphological changes of C. albicans, we performed real-time PCR and phase contrast microscopy. All the groups added vinegar drink showed the inhibitory effect of C. albicans on growth compared to the control. The expression of genes ALS3, ECE1, HWP1, and Sap5 were decreased by vinegar drink. As a result of phase contrast microscopy, the group to which vinegar drink was added showed significant quantitative decrease, morphological change and inhibition of C. albicans. This study can be provided as basic data for the development of antibiotics by verifying the antifungal activity of vinegar drinks.
Keywords
Vinegar drink; Candida albicans; Antifungal; Convergence;
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Times Cited By KSCI : 2  (Citation Analysis)
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