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http://dx.doi.org/10.15207/JKCS.2017.8.1.035

Development of bio-fusion materials with skin penetrating property derived from Aurelia aurita  

Kim, Hyoung Sik (BIO-FD&C Co.,Ltd.)
Seo, Hyo Hyun (BIO-FD&C Co.,Ltd.)
Lee, Seo-Hui (Department of Hospital Management, Konyang University)
Lim, Hyun Jung (Department of Hospital Management, Konyang University)
Shin, Jeong Won (Department of Hospital Management, Konyang University)
Kim, Seop Ri (Department of Hospital Management, Konyang University)
Moh, Sang Hyun (BIO-FD&C Co.,Ltd.)
Kim, Kwang-Hwan (Department of Hospital Management, Konyang University)
Publication Information
Journal of the Korea Convergence Society / v.8, no.1, 2017 , pp. 35-42 More about this Journal
Abstract
Previously, we reported LVH peptiede derived from Aurelia aurita as cosmecetuticals with anti-winkle activity. In this study, we synthesized pal-LVH using palmitic acid to enhance skin permeability of LVH and examined the effects as cosmeceuticals of pal-LVH. To evaluate these effects, we performed cell toxicity, wound healing, and patch test for skin irritation with LVH and pal-LVH and compared these results for their effects. As a result. pal-LVH was not showed in cytotoxicity and allergenic effect like as LVH. Besides, pal-LVH had almost same excellent anti-ageing properties in high concentration and anti-winkle effect in low concentrationwas as LVH. These results suggested synthesis of palimitic acid and LVH did not affect any functions as cosmeceuticals with increasing skin permeability. Therefore, pal-LVH can be adaptable as new cosmecetuticals with anti-winkle and anti-ageing materials and applied in the development of medicine through various convergence study.
Keywords
Convergence; Anti-ageing; Peptides; Palmitic acid; Percutaneous absorption; Aurelia aurita;
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Times Cited By KSCI : 1  (Citation Analysis)
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