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http://dx.doi.org/10.15207/JKCS.2015.6.5.077

Study on Convergence Technique Using the Antimicrobial Resistance and Virulence Genes Analysis in Escherichia coli  

Han, Jae-Il (Department of Public Health, Graduate School of Dankook University)
Sung, Hyun-Ho (Department of Clinical Pathology, Dongnam University)
Park, Chang-Eun (Department of Biomedical Laboratory Science, Namseoul University)
Publication Information
Journal of the Korea Convergence Society / v.6, no.5, 2015 , pp. 77-84 More about this Journal
Abstract
This study was conducted to investigate the characteristics of antibiotic resistant E. coli. its antibiotic susceptibility and pathogenicity were analyzed via molecular convergence technique, for the relationship of antibiotic susceptibility and pathogenicity. The 60 isolated strains consisted of ESBL(+)(8) and ESBL(-)(52) strains. The ESBL(+)(8) strains consisted of 2 strains without a pathogenic gene, stb(3), flich7(1), and flich7-eae(2). The ESBL(-)(52) strains consisted of 26 strains without a pathogenic gene, stx1(3), stb(10), flich7(2), eae(2), stx1-flich7(2), stx1-stb(4), flich7-stb(2), and flich7-stb-eae(1). In conclusion, antibiotic resistance is increasingly, Focused on molecular convergence, showed the correlation of pathogenicity with antibiotic resistance was poor. However, It will be able to find the exact pathogenic factor in the future through convergence technique including the analysis of virulence genes.
Keywords
Antimicrobial resistence; Convergence technique; Escherichia coli; Extended-spectrum beta-lactamases; Virulence genes;
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