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Pyriproxyfen Inhibits Hemocytic Phagocytosis of the Beet Armyworm, Spodoptera exigua  

Madanagopal, Nalini (Department of Bioresource Sciences, Andong National University)
Lee, Yong-Joon (Department of Bioelectric Engineering, Andong National University)
Kim, Yong-Gyun (Department of Bioresource Sciences, Andong National University)
Publication Information
The Korean Journal of Pesticide Science / v.11, no.3, 2007 , pp. 164-170 More about this Journal
Abstract
The concept of innate immunity in insects which refers to the first line of host defense constitutes the humoral and cellular components which are involved in recognition and actively participate in the elimination of the intruding foreign micro- or macro-organisms. Several recent studies suggest that juvenile hormone (JH) modulates the cellular immune reactions in response to pathogen. In this study, pyriproxyfen (a JH agonist as an insect growth regulator) was tested in its any inhibitory effect on the immune reactions of the beet armyworm, Spodoptera exigua. To this end, five different hemocyte morphotypes of final instar S. exigua were identified by phase contrast microscopy. Plasmatocytes and granular cells, which constitute about 90% of the total hemocyte count, were prominently distinguished based on their basophilic/acidophilic nature using Giemsa stain. The role of pyriproxyfen on the functional ability of hemocytes was analyzed using FITC-labeled Providencia vermicola for the phagocytic potential of the hemocytes. Both granular cells and plasmatocytes exhibited phagocytosis behavior. Pyriproxyfen significantly inhibited the phagocytosis of both cell types, proposing its novel action as an immunosuppressant.
Keywords
hemocytes; immune; phagocytosis; pyriproxyfen; Spodoptera exigua;
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Times Cited By KSCI : 3  (Citation Analysis)
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