Browse > Article
http://dx.doi.org/10.9717/kmms.2014.17.5.566

Semi-automated Approach to Hippocampus Segmentation Using Snake from Brain MRI  

Al Shidaifat, Ala'a Ddin (Department of Computer Engineering, UHRC, Inje University)
Al-Shdefat, Ramadan (Dept. of Pharmaceutics, Salman Bin Abdulaziz University)
Choi, Heung-Kook (Department of Computer Engineering, UHRC, Inje University)
Publication Information
Abstract
The hippocampus has been known as one of the most important structure related to many neurological disorders, such as Alzheimer's disease. This paper presents the snake model to segment hippocampus from brain MRI. The snake model or active contour model is widely used in medical image processing fields, especially image segmentation they look onto nearby edge, localizing them accurately. We applied a snake model on brain MRI. Then we compared our results with an active shape approach. The results show that hippocampus was successfully segmented by the snake model.
Keywords
Hippocampus; Snake model; Segmentation; MRI; Active shape approach;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 S.Keihaninejad, R.A. Heckemann, I.S. Gousias, P. Aljabar, J.V. Hajnal, D. Rueckert, et. al. "Automatic Volumetry can Reveal Visually Undetected Disease Features on Brain MR Images in Temporal Lobe Epilepsy," Proceeding of the IEEE International Symposium on Biomedical Imaging, pp. 105-108, 2010.
2 J.I. Arribas, V.D. Calhoun, and T. Adali, "Automatic Bayesian Classification of Healthy Controls, Bipolar Disorder, and Schizophrenia using Intrinsic Connectivity Maps from fMRI Data," IEEE Transactions on Biomedical Engineering, Vol. 57, No. 12, pp. 2850-2860, 2010.   DOI
3 D. Shen, S. Moffat, S.M. Resnick, and C. Davatzikos, "Measuring Size and Shape of the Hippocampus in MR Images using a Deformable Shape Model," NeuroImage, Vol. 15, No. 2, pp. 422-434, 2002.   DOI   ScienceOn
4 X. Lu and S. Luo, "Segmentation of Hippocampus in MRI using Watersnakes," Proceeding of the IEEE International Conference on Complex Medical Engineering, pp. 552-555, 2007.
5 J. Webb, A. Guimond, P. Eldridge, D. Chadwick, J. Meunier, J.P. Thirion, et. al. "Automatic Detection of Hippocampal Atrophy on Magnetic Resonance Images," Magnetic Resonance Imaging, Vol. 17, pp. 1149-1161, 1999.   DOI
6 B. Ostlad and A. Tonp, "Encoding of a Priori Information in Active Contour Models," IEEE Transactions on Pattern Analysis Machine Intelligence, Vol. 18, No. 9, pp. 863-872, 1996.   DOI
7 S.C. Zhu and A. Yuille, "Region Competition: Unifying Snakes, Region Growing, and Bayes/MDL for Multiband Image Segmentation," IEEE Transactions on Pattern Analysis Machine Intelligence, Vol. 18, No. 9, pp. 884-900, 1996.   DOI   ScienceOn
8 C. Xu and J. Prince, "Snakes, Shapes, and Gradient Vector Flow," IEEE Transaction on Image Processing, Vol. 7, No. 3, pp. 359-369, 1998.   DOI   ScienceOn
9 ITK-SNAP, http://www.itksnap.org, 2013.
10 C. Held, R. Palmisano, L. Haberle, and T. Wittenberg, "Comparison of Parameter-adapted Segmentation Methods for Fluorescence Micrographs," Cytometry Part A., Vol. 79, No. 11, pp. 933-945, 2011.
11 H. Hampel, S.J. Teipel, T. Fuchsberger, N. Andreasen, J. Wiltfang, M. Otto, et. al. "Value of CSF Beta-amyloid1-42 and Tau as Predictors of Alzheimer's Disease in Patients with Mild Cognitive Impairment," Molecular Psychiatry, Vol. 9, No. 6, pp. 526-532, 2009.
12 N. Sengee, A. Sengee, A. Enkhbolor, and H. K. Choi, "Contrast Enhancement for Segmentation of Hippocampus on Brain MR Images," Journal of Korea Multimedia Society, Vol. 15, No. 12, pp. 1409-1416, 2012.   과학기술학회마을   DOI   ScienceOn
13 M. Kass, A. Witkin, and D. Terzopoulos, "Snakes: Active Contour Models," International Journal of Computer Vision, Vol. 1, No. 4, pp. 321-331, 1988.   DOI   ScienceOn
14 W.G. Jeon, Y.S. Izmantoko, J.H. Son, and H.K. Choi, "Hippocampus Volume Measurement for the Determination of MCI," Journal of Korea Multimedia Society, Vol. 15, No. 12, pp. 1449-1455, 2012.   과학기술학회마을   DOI
15 J.G. Csernansky, L. Wang, S. Joshi, J.P. Miller, M. Gado, D. Kido, et. al. "Early DAT is Distinguished from Aging by High-dimensional Mapping of the Hippocampus," Neurology, Vol. 55, pp. 1636-1643, 2000.   DOI
16 H.C. Strasser, J. Lilyestrom, E.R. Ashby, N.A. Honeycutt, D.J. Schretlen, A.E. Pulver, et. al. "Hippocampal and Ventricular Volumes in Psychotic and Nonpsychotic Bipolar Patients Compared with Schizophrenia Patients and Community Control subjects: A Pilot Study," Biological Psychiatry, Vol. 57, No. 6, pp. 633-639, 2005.   DOI   ScienceOn
17 M.J. Firbank, A.M. Blamire, M.S. Krishnan, A. Teodorczuk, P. English, A. Gholkar, et. al. "Atrophy is Associated with Posterior Cingulate White Matter Disruption in Dementia with Lewy bodies and Alzheimer's Disease," NeuroImage, Vol. 36, No. 1, pp. 1-7, 2007.   DOI
18 R. Brookmeyer, E. Johnson, K. Ziegler-Graham, and H.M. Arrighi, "Forecasting the Global Burden of Alzheimer's Disease," Alzheimer's and Dementia, Vol. 3, No. 3, pp. 186-191, 2007.   DOI   ScienceOn
19 F. Cendes, Z. Caramanos, F. Andermann, F. Dubeau, and D.L. Arnold, "Proton Magnetic Resonance Spectroscopic Imaging and Magnetic Resonance Imaging Volumetry in the Lateralization of Temporal Lobe Epilepsy: A Series of 100 Patiekts," Annals of Neurology, Vol. 42, No. 5, pp. 737-746, 1997.   DOI   ScienceOn
20 A. Enkhbolor, Y.S. Izmantoko, and H.K. Choi, "Comparison of Active Contour and Active Shape Approaches for Corpus Callosum Segmentation," Journal of Korea Multimedia Society, Vol. 16, No. 9, pp. 1018-1030, 2013.   과학기술학회마을   DOI   ScienceOn