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http://dx.doi.org/10.4014/mbl.1805.05014

In-vitro Anti-thrombosis Activities of Different Parts of Nelumbo nucifera Gaertner  

Ahn, Seon-Mi (Department of Food and Nutrition, Andong National University)
Sung, Hwa-Jung (Department of Food and Nutrition, Andong National University)
Kim, Jong-Sik (Department of Biological Science, Andong National University)
Park, Jong-Yi (Gyeongbuk Institute for Bio-Industry)
Sohn, Ho-Yong (Department of Food and Nutrition, Andong National University)
Publication Information
Microbiology and Biotechnology Letters / v.46, no.4, 2018 , pp. 372-376 More about this Journal
Abstract
To investigate the bio-activities of lotus (Nelumbo nucifera Gaertner), ethanol extracts were prepared from different parts of lotus, including lotus root, node of root (NR), leaf, pod of seed (PS), seed (S), and embryo of seed (ES), respectively. Anti-thrombosis activities were evaluated. NR, S, and PS extracts displayed strong anti-coagulation activities, as evidenced by the inhibition of thrombin, prothrombin, and coagulation factors, respectively. NR, leaf, S, and PS extracts displayed strong platelet aggregation inhibitory activities. The aggregation inhibition of S and PS extract was comparable to that of aspirin. The extracts of NR, S, and PS did not show hemolysis activity up to 1.0 mg/ml.
Keywords
Anti-coagulation; anti-platelet aggregation; lotus; Nelumbo nucifera Gaertner;
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Times Cited By KSCI : 3  (Citation Analysis)
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