Detection of Novel Polyketide Synthase Genes in Sorangium cellulosum Isolated in Korea
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Youn, Jin-Kwon
(Myxobacteria Bank, Department of Biotechnology, Hoseo University)
Kim, Do-Hee (Myxobacteria Bank, Department of Biotechnology, Hoseo University) Lee, Han-Bit (Myxobacteria Bank, Department of Biotechnology, Hoseo University) Lee, Kye-Won (Myxobacteria Bank, Department of Biotechnology, Hoseo University) Cho, Kyung-Yun (Myxobacteria Bank, Department of Biotechnology, Hoseo University) |
1 | Julien, B., Z. Q. Tian, R. Reid, and C. D. Reeves. 2006. Analysis of the ambruticin and jerangolid gene clusters of Sorangium cellulosum reveals unusual mechanisms of polyketide biosynthesis. Chem. Biol. 13: 1277-1286. DOI ScienceOn |
2 | Weissman, K. J. and R. Müller. 2009. A brief tour of myxobacterial secondary metabolism. Bioorg. Med. Chem. 17: 2121-2136. DOI ScienceOn |
3 | Schneiker, S., O. Perlova, O. Kaiser, K. Gerth, A. Alici, M. O. Altmeyer, D. Bartels, T. Bekel, S. Beyer, E. Bode, H. B. Bode, C. J. Bolten, J. V. Choudhuri, S. Doss, Y. A. Elnakady, B. Frank, L. Gaigalat, A. Goesmann, C. Groeger, F. Gross, L. Jelsbak, L. Jelsbak, J. Kalinowski, C. Kegler, T. Knauber, S. Konietzny, M. Kopp, L. Krause, D. Krug, B. Linke, T. Mahmud, R. Martinez-Arias, A. C. McHardy, M. Merai, F. Meyer, S. Mormann, J. Munoz-Dorado, J. Perez, S. Pradella, S. Rachid, G. Raddatz, F. Rosenau, C. Ruckert, F. Sasse, M. Scharfe, S. C. Schuster, G. Suen, A. Treuner-Lange, G. J. Velicer, F.J. Vorholter, K. J. Weissman, R. D. Welch, S. C. Wenzel, D. E. Whitworth, S. Wilhelm, C. Wittmann, H. Blocker, A. Puhler, and R. Muller. 2007. Complete genome sequence of the myxobacterium Sorangium cellulosum. Nat. Biotechnol. 25: 1281-1289. DOI ScienceOn |
4 | Sambrook, J., E. F. Fritsch and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y. |
5 | Li, Z. F., J. Y. Zhao, Z. J. Xia, J. Shi, H. Liu, Z. H. Wu, W. Hu, W. F. Liu, and Y. Z. Li. 2007. Evolutionary diversity of ketoacyl synthases in cellulolytic myxobacterium Sorangium. Syst. Appl. Microbiol. 30: 189-196. DOI ScienceOn |
6 | Hyun, H., J. Chung, H. Lee, J. Youn, C. Lee, D. Kim, and K. Cho. 2009. Isolation of cellulose-degrading myxobacteria Sorangium cellulosum. Kor. J. Microbiol. 45: 48-53. |
7 | Gerth, K., S. Pradella, O. Perlova, S. Beyer, and R. Muller. 2003. Myxobacteria: proficient producers of novel natural products with various biological activities-past and future biotechnological aspects with the focus on the genus Sorangium. J. Biotech. 106: 233-253. DOI |
8 | Bode, H. B. and R. Müller. 2006. Analysis of myxobacterial secondary metabolism goes molecular. J. Ind. Microbiol. Biotechnol. 33: 577-588. DOI ScienceOn |
9 | Gerth, K., O. Perlova, and R. Muller. 2008. Sorangium cellulosum. pp. 329-348. In Whitworth, D. E. (ed.), Myxobacteria: multicellularity and differentiation. ASM Press, Washington, D.C. |
10 | Staunton, J. and K. J. Weissman. 2001. Polyketide biosynthesis: a millennium review. Nat. Prod. Rep. 18: 380-416. DOI ScienceOn |
11 | Staunton, J. and B. Wilkinson. 2001. Combinatorial biosynthesis of polyketides and nonribosomal peptides. Curr. Opin. Chem. Biol. 5: 159-164. DOI ScienceOn |
12 | Reichenbach, H. and M. Dworkin. 1992. The myxobacteria. pp. 3416-3487. In Balows, A., H.G. Trüper, M. Dworkin, W. Harder, and K.-H. Schleifer (ed.), The Prokaryotes, 2nd ed., vol. IV, Springer Verlag, NY. |
13 | Ronning, C. M. and W. C. Nierman. 2008. The genomes of Myxococcus xanthus and Stigmatella aurantiaca, pp. 285-298. In Whitworth, D. E. (ed.), Myxobacteria: multicellularity and differentiation. ASM Press, Washington, D.C. |
14 | Reichenbach, H. 2005. Myxococcales. pp. 1059-1144. In Brenner, D.J., N.R. Krieg, J.T. Staley, and G.M. Garrity (ed.), Bergey's Manual of Systematic Bacteriology, 2nd ed. Bergey's Manual Trust, East Lansing, MI. |
15 | Hyun, H., J. Chung, J. Kim, J. S. Lee, B. -M. Kwon, K. -H. Son, and K. Cho. 2008. Isolation of Sorangium cellulosum carrying epothilone gene clusters. J. Microbiol. Biotechnol. 18: 1416-1422. |
16 | Schirmer, A., R. Gadkari, C. D. Reeves, F. Ibrahim, E. F. DeLong, and C. R. Hutchinson. 2005. Metagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissoluta. Appl. Environ. Microbiol. 71: 4840-4849. DOI ScienceOn |
17 | Frank, B., J. Knauber, H. Steinmetz, M. Scharfe, H. Blocker, S. Beyer, and R. Müller. 2007. Spiroketal polyketide formation in Sorangium: identification and analysis of the biosynthetic gene cluster for the highly cytotoxic spirangienes. Chem. Biol. 14: 221-233. DOI ScienceOn |
18 | Johnson, M., I. Zaretskaya, Y. Raytselis, Y. Merezhuk, S. McGinnis, and T. L. Madden. 2008. NCBI BLAST: a better web interface. Nucleic Acids Res. 36: W5-W9. DOI ScienceOn |
19 | Larkin, M. A., G. Blackshields, N. P. Brown, R. Chenna, P. A. McGettigan, H. McWilliam, F. Valentin, I. M. Wallace, A. Wilm, R. Lopez, J. D. Thompson, T. J. Gibson, and D. G. Higgins. 2007. Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948. DOI ScienceOn |
20 | Komaki, H., R. Fudou, T. Iizuka, D. Nakajima, K. Okazaki, D. Shibata, M. Ojika, and S. Harayama. 2008. PCR detection of type I polyketide synthase genes in myxobacteria. Appl. Environ. Microbiol. 74: 5571-5574. DOI ScienceOn |
21 | Finking, R. and M. A. Marahiel. 2004. Biosynthesis of nonribosomal peptides. Annu. Rev. Microbiol. 58: 453-488. DOI ScienceOn |
22 | Cane, D. E., C. T. Walsh, and C. Khosla. 1998. Harnessing the biosynthetic code: combinations, permutations, and mutations. Science 282: 63-68. DOI |
23 | Kim, Y. S., W. C. Bae, and S. J. Back. 2003. Bioactive substances from myxobacteria. Kor. J. Microbiol. Biotechnol. 31: 1-12. |
24 | Julien, B., S. Shah, R. Ziermann, R. Goldman, L. Katz, and C. Khosla. 2000. Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum. Gene 16: 153-160. |
25 | Molnar, I., T. Schupp, M. Ono, R. Zirkle, M. Milnamow, B. Nowak-Thompson, N. Engel, C. Toupet, A. Stratmann, D. D. Cyr, J. Gorlach, J. M. Mayo, A. Hu, S. Goff, J. Schmid, and J. M. Ligon. 2000. The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90. Chem. Biol. 7: 97-109. DOI ScienceOn |
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