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Antibaterial Activity of Persicaria hydropiper Extracts and Its Application for Cosmetic Material  

Kim, Jung-Eun (Department of Fine Chemistry, Research Center for Development of Green Cosmetic, College of Nature and Life Science, Seoul National University of Technology)
Kim, Eun-Hee (Department of Fine Chemistry, Research Center for Development of Green Cosmetic, College of Nature and Life Science, Seoul National University of Technology)
Park, Soo-Nam (Department of Fine Chemistry, Research Center for Development of Green Cosmetic, College of Nature and Life Science, Seoul National University of Technology)
Publication Information
Microbiology and Biotechnology Letters / v.38, no.1, 2010 , pp. 112-115 More about this Journal
Abstract
In this study, the antibacterial activity and the moisturizing effect of cream contaning Persicaria hydropiper L. extract were investigated by clinical trial. MIC values of ethyl acetate fraction from Persicaria hydropiper on P.acnes, S.aureus, P.ovale were 0.13~0.25%. The results showed that the antibacterial activity of the ethyl acetate fraction was higher than or equal to the methyl paraben and quercetin. The cream containing the ethyl acetate fraction of Persicaria hydropiper L. extracts was formulated for skin hydration effect. Also, the transepidermal water loss (TEWL) and the water contents in skin were measured. The cream containing Persicaria hydropiper L. extract was applied to the right lower arm. After 180 min, TEWL of parts was decreased as $6.5\;g/m^2h$ (experimental cream) and $7.5\;g/m^2h$ (placebo cream) respectively. And the water contents in skin were increased by 2~4% than the placebo cream. These results indicate that extract/fractions of Persicaria hydropiper L. can function as high potential as bactericide against the skin pathogenic bacteria and the increase of skin hydration of the cream containing extract could be applicable to new functional cosmetics for antiaging.
Keywords
Persicaria hydropiper; antibacterial activity; skin hydration; cosmetics; methyl paraben;
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