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Screening of Antimicrobial Substances against Brachyspira hyodysenteriae  

Kim, Jin-Gyu (Department of Biotechnology)
O, Se-Taek (Konkuk University)
Yang, Si-Yong (Department of Biotechnology)
Kim, Seon-Yeo (Konkuk University)
Gang, Hyeon-Mi (Department of Biotechnology)
Mun, Jin-San (Konkuk University)
Song, Min-Dong (Graduate School of East-West Medical Science, Kyunghee University)
Publication Information
Microbiology and Biotechnology Letters / v.32, no.4, 2004 , pp. 352-355 More about this Journal
Abstract
The extracts from 70 different plant natural products were used to investigate the antimicrobial activities against Brachyspira hyodrsenteriae, the causative agent of swine dysentery. Among them, the extracts from Terminalia chehula exhibited the highest antimicrobial activities against B. hyodysenteriae. It showed the antimicrobial activity against B. hyodysensteriae mostly in parts of its shell. Minimum inhibitory concentration (MIC) of the water extracts of T chehula was 12.5 mg/ml. After organic solvent extractions, the ethylacetate extracts exhibited higher antimicrobial activities against B. hyodysenteriae, and their antimicroactivities were similar to that of the tannin. In conclusion, these findings suggest that the extracts from T chebula may be used as animal feed additives for their antimicrobial activities against B. hyodysenteriae.
Keywords
Brachyspira hyodysenteriae; Terminalia chebula; antimicrobial activity;
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