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Isolation of Polyene Antifungal Antibiotics Against Gummy Stem Light Caused by Didymella bryoniae  

김광석 (경북대학교 미생물학과)
서영배 (경북대학교 미생물학과)
Publication Information
Microbiology and Biotechnology Letters / v.32, no.3, 2004 , pp. 238-242 More about this Journal
Abstract
Antifungal agents, flavofungin and fungichromin were isolated from the fermentation culture broth of a Streptomyces sp. SKM338. Biological evaluation of these antibiotics indicated that the compounds possesses broad spectrum antifungal activity against various pathogens. Especially, these compounds inhibited throughly growth of Didymella bryoniae, caused Gummy stem blight of melons, occurs in the southeastern Korea. Inhibition of this pathogen may be prevented from directly reducing both pre- and post-harvest yields.
Keywords
Didymella bryoniae; antifungal substance; polyene; flavofungin; fungichromin; filipins;
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