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Basic Physiological Activities of Bifidobacterium infantis Maeil-K9 and Lactobacillus plantarum KCTC3099 Selected by Anticarcinogenic Activities.  

김응률 (매일유업(주)중앙연구소)
정병문 (매일유업(주)중앙연구소)
김지연 (서울대학교 식품공학과)
김서영 (서울대학교 식품공학과)
정후길 (매일유업(주)중앙연구소)
이형주 (서울대학교 식품공학과)
전호남 (매일유업(주)중앙연구소)
Publication Information
Microbiology and Biotechnology Letters / v.31, no.4, 2003 , pp. 348-354 More about this Journal
Abstract
This study was conducted to confirm the availability of lactic acid bacteria as probiotics haying inhibitory effects to cancer cell line. Five lactic acid bacteria showing anti-cancer activity were compared by acid tolerance, bile tolerance, antibiotics resistance, milk fermentation, stability, and cell adherence activity to colon epithelial cell. The results obtained are as follows : In acid tolerance, all strains did not have a resistance below pH 3.0 and 3.5 except Lactobacillus plantarum KCTC3099. In antibiotics resistance, Lactococcus lactis and L. plantarum KCTC3099 were resistant to cotrimoxazol (128 mg/1), and Bifidobacterium adolescentis Maeil-K8 and B. infantis Maeil-K9 were resistant to doxycylin and gentamycin (4 mg/1). In case of cell adherence ability to Caco-2 cell, B. infantis Maeil-K9 was found to be superior to others as 3.1%, while the others were less than 0.5%. When the strains were cultured to milk base, viable counts of the strains tested increased more 1 log cycle than inoculation, but acid production was very low except L. plantarum KCTC3099. Also, L. plantarum KCTC3099, B. adolescentis Maeil-K8, and B. infantis Maeil-K9 were stable in fermented milk base during storage. In conclusion, L. plantarum KCTC3099 and B. infantis Maeil-K9 were confirmed to be superior for the availability as probiotics.
Keywords
Bifidobacterium infantis Maeil-K9; Lactobacillus plantarum KCTC3099; anticarcinoma; probiotics;
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Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By SCOPUS : 3
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