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Bioactive Substances from Myxobacteria.  

김용석 (일양약품 중앙연구소 생물공학팀)
배우철 (일양약품 중앙연구소 생물공학팀)
백성진 (일양약품 중앙연구소 생물공학팀)
Publication Information
Microbiology and Biotechnology Letters / v.31, no.1, 2003 , pp. 1-12 More about this Journal
Abstract
Myxobacteria are soil bacteria that move by gliding and have a complicated life cycle. In the research over the 25 years the myxobacteria have been shown to be a rich source of potentially useful bioactive substances. So far about 80 different basic compounds and 450 structural variants have been characterized. It is remarkable that myxobacteria produce the substance has special mechanisms. 26 new electron transport inhibitors,5 inhibitors of nucleic acid polymerases, 10 substances that act on the cytoskeleton, and 1 inhibitor of fungal acetyl-CoA carboxylase have been found. Presently, large-scale technical process was not fully established. But one of the compounds from myxobacteria is able to pass the many thresholds, which are on the road to application.
Keywords
Myxobacteria; source of bioactive compounds; isolation; fermentation;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By SCOPUS : 9
연도 인용수 순위
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