Isolation and Purification of an Antitumor Metabolite from Alternaria brassicicola SW-3, the Cause of Brassica Black Leaf Spot Disease. |
나여정
(서울여자대학교 식품ㆍ미생물공학과)
이방숙 (서울여자대학교 화학과) 남궁성건 (서울여자대학교 화학과) 정동선 (서울여자대학교 식품ㆍ미생물공학과) |
1 | Tsuruo, T., T. OH-hara, H. lida, S. Tsukagoshi, Z. Sato, I. Matsuda, S. Iwasaki, F. Shimizu, K. Sasagawa, M. Fukami, K. Fukuda, and M. Arakawa. 1986. Rhizoxin, a macrocyclic lactone antibiotic, as a new antitumor agent against human and murine tumor cells and their vincristine-resistant sublines. Cancer Res. 46: 381-385. |
2 | Privalsky, M. L. 1998. Depudecin makes a debut Proc. Nat!. Acad. Sci. USA. 95: 3335-7. DOI ScienceOn |
3 | Tanaka, M., T. Fujimori, and K. Nabeta. 2000. Biosynthesis of depudecin, a metabolite of Nimbya scirpicola. Biosci. Biotechno!. Biochem. 64: 244-247. |
4 | Scudiero, D. A, R. H. Shoemaker, K. D. Paul, A Monks, S. Tierney, T. H. Nofziger, M. J. Currens, D. Seniff, and M. R. Boyd. 1988. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cacer Res. 48: 4827-4833. |
5 | Tanaka, M., J. Ohra, Y. Tsujino, Y. Sawaji, and T. Fujimori. 1994. Phytotoxin produced by Nimbya scirpicola. Biosci. Biotechnol. Biochem. 58: 565-566. |
6 | Isaka, M. A Jaturapat, W. Kladwang, J. Punya, Y. Lertwerawat, M. Tanticharoen, and Y. Thebtaranonth. 2000. Antiplasmodial compounds from the wood-decayed fungus Xylaria sp. BCC 1067. Planta Med. 66: 473-475. |
7 | Han, J W, S. H. Ahn, S. H. Park, S. Y. Wang, G. U. Bae, D. W. Seo, H. K. Kim, S. Hong, H. Y. Lee, Y. W. Lee, and H. W. Lee. 2000. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin. Cancer Res. 60: 6068-6074. |
8 | Satoshi Omura. 1992. The search for bioactive compounds from microorganisms, Springer Verlag, New York. |
9 | Udagawa, T., J. Yuan, D. Panigraphy, Y. H. Chang, J. Shah, and R. J. D'Amato. 2000. Cytochalasin E, an epoxide containing Aspel;gillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. .J Pharmacol Exp. Ther. 294: 421 -427. |
10 | Ciegler, A and A Laxdenfelser. 1969. An antibiotics complex from A. brassicicola. Experienta 25: 719. |
11 | Oikawa, T., C. Onozawa, M. Inose, and M. Sasaki. 1995. Depudecin, a microbial metabolite containing two epoxide groups, exhibits anti-angiogenic activity in vivo. Bioi. Pharm. Bull. 18: 1305. |
12 | Kwon, H. J., T. Owa, C. A Hassig, J. Shimada, and S. L. Schreiber. 1998. Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase. Proc. Natl. Acad. Sci. USA 95: 3356-3361. |
13 | Miyadaoh, S. 1993. Research on antibiotics screening in Japan over the last decade: a producing microorganism approach. J Actinomycetol. 7: 100-106. |
14 | King, A D. Jr. and J. E. Shade. 1984. Alternaria toxins and their importance in food. .J Food Prot. 47: 886. |
15 | Rotem, J. 1994. The Genus Alternaria, biology, epidemiology and pathogenicity. APS press, St. Paul, MN |
16 | Shimada, J., H. J. Kwon, Sawamura M., and S. L. Schreiber. 1995. Synthesis and cellular characterization of the detransformation agent, (-)-depudecin. ChemBioi 2: 517-25. |
17 | Matsumoto, M., S. Matsutani, K. Sugita, H. Yoshida, F. Hayashi, Y. Terui, H. Nakai, N. Uotani, Y. Kawamura, K. Matsumoto, J Shoji, and T. Yoshida. 1992. Depudecin: a novel compound inducing the flat phenotype of NIH3T3 cells doubly transformed by ras- and src-oncogene, produced by Alternaria brassicicola. .J Antibiotcs 45: 879-885. |