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Current Status on Molecular Genetic Study and Comparative Genomic Analysis of Virulence Related Genes in Xanthomonas oryzae pv. oryzae  

Kang, Hee-Wan (Graduate School of Biotechnology and Information Technology, Hankyong National University)
Park, Young-Jin (National Institute of Agricultural Biotechnology)
Lee, Byeong-Moo (National Institute of Agricultural Biotechnology)
Publication Information
Korean Journal of Microbiology / v.44, no.1, 2008 , pp. 1-9 More about this Journal
Abstract
Xanthomonas oryzae pv. oryzae (Xoo) is the causal agent of bacterial blight on rice. In this paper, current status on molecular genetic study of major virulence genes, hypersensitive response and pathogenicity (hrp), productions of extracellular polysaccharide (EPS), extracellular enzymes and lipopolysaccharides (LPS), avr genes were reviewed. The IS elements with 611 copies including 133 ORF IS were inserted in various regions of the Xoo genome and in expecially regions franking virulence genes. Whole genome sequence of X. oryzae pv. oryzae KACC10331 were used for defining genetic organization of the virulence genes. Futhermore, the virulence genes in Xoo genome were compared to those of other Xanthomonas species in Blast GenBank data base.
Keywords
comparative sequence; molecular genetics; review; virulence genes; Xanthomonas oryzae pv. oryzae;
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1 Chan, J.W. and P.H. Goodwin. 1999. The molecular genetics of virulence of Xanthomonas campestris. Biotech. Advan. 17, 489-580   DOI   ScienceOn
2 Ezuka, A and H. Kaku. 2000. A historical review of bacterial blight of rice. Bull. Natl. Inst. Agrobiol. Resour. Japan 15, 1-207
3 Gophna, U., E.Z. Ron, and D. Graur. 2003. Bacterial type III secretion systems are ancient and evolved by multiple horizontal-transfer events. Gene 312, 151-163   DOI   ScienceOn
4 Hu, J., W. Qian, and C.Z. He. 2007. The Xanthomonas oryzae pv. oryzae eglXoB endoglucanase gene is required for virulence to rice. FEMS Microbiol. Lett. 269, 273-279   DOI   ScienceOn
5 Huguet, E. and U. Bonas. 1997. hrpF of Xanthomonas campestris pv. vesicatoria encodes an 87-kDa protein with homology to NolX of Rhizobium fredii. Mol. Plant-Microbe Interact. 10, 488-498   DOI   ScienceOn
6 Jha, G., R. Rajeshwari, and R.V. Sonti. 2005. Bacterial type two secretion system secreted proteins: double-edged swords for plant pathogens. Mol. Plant-Microbe Interact. 18, 891-898   DOI   ScienceOn
7 Katzen, F., A. Becker, A. Zorreguieta, A. Puhler, and L. Ielpi. 1996. Promoter analysis of the Xanthomonas campestris pv. campestris gum operon directing biosynthesis of the xanthan polysaccharide. J. Bacteriol. 178, 4313-4318   DOI   PUBMED
8 Leigh, J.A. and D.L. Coplin. 1992. Exopolysaccharides in plant-bacterial interactions. Annu. Rev. Microbiol. 46, 307-346   DOI   ScienceOn
9 Simpson, A.J.G., F.C. Reinach, P. Arruda, F.A. Abreu, M. Acencio, R. Alvarenga, L.M.C. Alves, J.E. Araya, G.S. Baia, C.S. Baptista, et al. 2000. The genome sequence of the plant pathogen Xylella fastidiosa. Nature 406, 151-157   DOI   ScienceOn
10 Vorholter, F.J., K. Niehaus, and A. Puhler. 2001. Lipopolysaccharide bilsynthesis in Xanthonnas campestris pv. campestris: a cluster of 15 genes is involved in the biosynthesis of the LPS O-antigen and the LPS core. Mol. Genet. Genom. 266, 79-95   DOI
11 Wengelnik, K., G. Van Den Ackerveken, and U. Bonas. 1996. HrpG, a key hrp regulatory protein of Xanthomonas campestris pv. vesicatoria is homologous to two-component response regulators. Mol. Plant-Microbe Interact. 9, 704-712   DOI   PUBMED   ScienceOn
12 Willis, D.K., J.J. Rich, and E.M. Hrabak. 1991. hrp Genes of phytopathogenic bacteria. Mol. Plant-Microbe Interact. 4, 132-138   DOI
13 Shen, Y. and P. Ronald. 2002. Molecular determinants of disease and resistance in interactions of Xanthomonas oryzae pv. oryzae and rice. Microbe Infect. 4, 1361-1367   DOI   ScienceOn
14 Wood, D.W., J.C. Setubal, and R. Kaul. 2001. The genome of the natural genetic engineer Agrobacterium tumefaciens C58. Science 294, 2317-2323   DOI   ScienceOn
15 Koplin, R., G. Wang, B. Hotte, U.B. Priefer, and A. Puhler. 1993. A 3.9-kb DNA region of Xanthomonas campestris pv. campestris that is necessary for lipopolysaccharide production encodes a set of enzymes involved in the synthesis of dTDP-rhanmose. J. Bacteriol. 175, 7786-7792   DOI   PUBMED
16 Tang, J.L., Y.N. Liu, C.E. Barber, J.M. Dow, J.C. Wootton, and M.J. Daniels. 1991. Genetic and molecular analysis of a cluster of rpf genes involved in positive regulation of synthesis of extracellular enzymes and polysaccharide in Xanthomonas campestris pathovar campestris. Mol. Gen. Genet. 226, 409-417   PUBMED
17 Mew, T.W., A.M. Alvarez, J.E. Leach, and J. Swing. 1993. Focus on bacterial blight of rice. Plant Disease 77, 5-12   DOI
18 Vojnov, A.A., A. Zorreguieta, J.M. Dow, M.J. Daniels, and M.A. Dankert. 1998. Evidence for a role for the gumB and gumC gene products in the formation of xanthan from its pentasaccharide repeating unit by Xanthomonas campestris. Microbiology 144, 1487-1493   DOI   ScienceOn
19 Barras, F. 1994. Exracellular enzymes and pathogenesis of soft-rot Erwinia. Annu. Rev. Phytopath. 32, 201-234   DOI   ScienceOn
20 Shen, Y., P. Sharma, F.G. Da Silva, and P. Ronald. 2002. The Xanthomonas oryzae pv. oryzae raxP and raxQ genes encode an ATP sulphurylase and adenosine-5'-phosphosulphate kinase that are required for AvrXa21 avirulence activity. Mol. Microbiol. 44, 37-48   DOI   ScienceOn
21 Burdman, S., Y. Shen, S.W. Lee, Q. Xue, and P. Ronald. 2004. RaxH/RaxR: A two-component regulatory system in Xanthomonas oryzae pv. oryzae required for AvrXa21 activity. Mol. Plant-Microbe Interact. 17, 602-612   DOI   ScienceOn
22 Keyu, Gu., B. Yang, D. Tian, L. Wu, D. Wang, C. Sreekala, F. Yang, Z. Chul, G.L. Wang, F.F. White, and Z. Yin. 2005. R gene expression induced by a type-III effector triggers disease resistance in rice. Nature 435, 1122-1125   DOI   ScienceOn
23 Patil, P.B. and R.V. Sonti. 2004. Variation suggestive of horizontal gene transfer at a lipopolyasccharde (lps) biosynthetic locus in Xanthomonas oryzae pv. oryzae, the bacterial leaf blight pathogen of rice. BMC Microbiol. http://.biomedcentral.com/1471-2180/4/40
24 Buttner, D., D. Nennstiel, B. Klusener, and U. Bonas. 2002. Functional analysis of HrpF, a putative type III translocon protein from Xanthomonas campestris pv. vesicatoria. J. Bacteriol. 184, 2389-2398   DOI
25 Park, Y.J. 2007. Functional analysis of gene cluster of lipopolysaccharide biosynthesis in Xanthomonas oryzae pv. oryzae. Ph. D. thesis. Hankyong National University, Republic of Korea
26 Dow, J.M., A.E. Osbourn, T.J. Wilson, and M.J. Daniels. 1995. A locus determining pathogenicity of Xanthomonas campestris is involved in lipopolysaccharide biosynthesis. Mol. Plant-Microbe Interact. 8, 768-777   DOI   PUBMED
27 Newman, M.A, M.J. Daniels, and J.M. Dow. 1995. Lipopolysaccharide from Xanthomonas campestris induces defense-relaged gene expression in Brassica campestris . Mol Plant-Microbe Interact. 8, 778-780   DOI   PUBMED
28 Ryba, W., M.N. Sakthivel, C. Yun, R. White, and J.E. Leach. 2005. Identification and characterization of IS1112 and IS1113 insertion element sequences in Xanthomonas oryzae pv. oryzae. DNA Seq. 16, 75-79   DOI   PUBMED
29 Xiao, Y., Y. Lu, S. Heu, and S.W. Hutcheson. 1992. Organization and environmental regulation of the Pseudomonas syringae pv. syringae 61 hrp cluster. J. Bacterial. 174, 1734-1741   DOI
30 Yang, B. and F. White. 2004. Diverse members of the AvrBs3/PthA family of type III effectors are major virulence determinants in bacterial blight disease of rice. Mol. Plant-Microbe Interact. 17, 1192-1200   DOI   ScienceOn
31 Ray, S.K., R. Rajeshwari, and R.V. Sonti. 2000. Mutants of Xanthomonas oryzae pv. oryzae deficient in general secretory pathway are virulence deficient and unable to secret xylanase. Mol. Plant-Microbe Interact. 13, 394-40112   DOI   ScienceOn
32 Buell, C.R, V. Joardar, M. Lindeberg, J. Selengut, I.T. Paulsen, M.L. Gwinn, R.J. Dodson, R.T. Deboy, A.S. Durkin, J.F. Kolonay, R Madupu, et al. 2003. The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000. Proc. Natl. Acad. Sci. USA 100, 10181-10186
33 Rajeshwari, R., G. Jha, and R.V. Sonti. 2005. Role of an in planta-expressed xylanase of Xanthomonas oryzae pv. oryzaein promoting virulence on rice. Mol Plant-Microbe Interact. 18, 830-837   DOI   ScienceOn
34 Hopkins, C.M., F.F. White, S. Choi, A. Guo, and J.E. Leach. 1992. Identification of a family of avirulence genes from Xanthomonas oryzae pv. oryzae. Mol. Plant-Microbe Interact. 5, 451-459   DOI   PUBMED
35 McNeil, M., A.G. Darvill, S.C. Fry, and P. Albersheim. 1984. Structure and function of the primary-cell walls of plants. Annu. Rev. Biochem. 53, 625-663   DOI   ScienceOn
36 Tsuge, S., S. Terashima, A. Furutani, H. Ochiai, T. Oku, K. Tsuno, H. Kaku, and Y. Kubo. 2005. Effects on promoter activity of base substitutions in the cis-acting regulatory element of HrpXo regulons in Xanthomonas oryzae pv. oryzae. J. Bacteriol. 187, 2308-2314   DOI   ScienceOn
37 White, F.F., B. Yang, and L.B. Johnson, 2000. Prospects for understanding avirulence gene function. Curr. Opin. Plant Biol. 3, 291-298   DOI   ScienceOn
38 Adhikari, T.B., T.W. Mew, and J.E. Leach. 1999. Genotypic and pathotypic diversity in Xanthomonas oryzae pv. oryzae in Nepal. Phytopathol. 89, 687-694   DOI   ScienceOn
39 Salanoubat, M., S. Genin, F. Artiguenave, J. Gouzy, S. Mangenot, M. Arlat, A. Billault, P. Brottier, J.C. Camus, L. Cattolico, et al. 2002. Genome sequence of the plant pathogen Ralstonia solanacearum. Nature 415, 497-502   DOI   ScienceOn
40 Fernadez, M., W. Van Doesburg, G.A.M. Rutten, J.D. Marugg, A.C. Alting, R. Van Krannenburg, and O.P. Kuipers. 2000. Molecular and functional analyses of metC gene of Lactococcus lactis, encoding cystathionine gamma lyase. Appl. Environ. Microbiol. 66, 42-48   DOI
41 Kingsley, M.T., D.W. Gabriel, G.C. Marlow, and P.D. Toberts. 1993. The opsX locus of Xanthomonas campestris affects host range and biosynthesis of lipopolysaccharide and extracellular polysaccharide. J. Bacteriol. 175, 5839-5850   DOI   PUBMED
42 Skinner, T., W. Mew, and J.E. Leach. 1995. Genetic diversity of Xanthomonas oryzae pv. oryzae in Asia. Appl. Environ. Microbiol. 61, 966-971   PUBMED
43 Jha, G., R. Rajeshwari, and R.V. Sonti. 2007. Functional interplay between two Xanthomonas oryzae pv. oryazae secretion systems in modulating virulence on rice. Mol. Plant-Microbe Interact. 20, 31-40   DOI   ScienceOn
44 Lee, B.M., Y.J. Park, D.S. Park, H.W. Kang, J.G. Kim, E.S. Song, I.C. Park, U.H. Yoon, J.H. Hahn, B.S. Koo, et al. 2005. The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the bacterial blight pathogen of rice. Nucleic Acids Res. 33, 577-586   DOI   ScienceOn
45 Wengelnik, K. and U. Bonas. 1996. HrpXv, an AraC-type regulator, activates expression of five out of six loci in the hrp cluster of Xanthomonas campestris pv. vesicatoria essential for pathogenicity and induction of the hypersensitive reaction. J. Bacteriol. 178, 3462-3469   DOI   PUBMED
46 Zhu, W., M.M. Magbanua, and F.F. White. 2000. Identification of two novel hrp-associated genes in the hrp gene cluster of Xanthomonas oryzae pv. oryzae. J. Bacteriol. 182, 1844-1853   DOI
47 Da Silva, A.C., J.A. Ferro, F.C. Reinach, C.S. Farah, L.R. Furlan, R.B. Quaggio, C.B. Monteiro-Vitorello, M.A. Van Sluys, N.F. Almeida, L.M. Alves, A.M. Do Amaral, et al. 2002. Comparison of genomes of two Xanthomonas pathogens with differing host specificities. Nature 417, 459-463   DOI   ScienceOn
48 Dow, J.M., L. Crossman, and K. Findlay, Y.Q. He, J.X. Feng, and J.L. Tang. 2003. Biofilm dispersal in Xanthomonas capestris is controlled by cell-cell signaling and is required for full virulence to plants. Proc. Natl. Acad. Sci. USA 100, 10995-12100
49 Dharmapuri, S., J. Yashitola, M.R. Vishnupriya, and R.V. Sonti. 2001. Novel genomic locus with atypical G+C content that is required for extracellular polysaccharide production and virulence in Xanthomonas oryzae pv. oryzae. Mol. Plant-Microbe Interact. 14, 1335-1339   DOI   ScienceOn
50 Galas, D.J. and M. Chandler. 1989. Bacterial insertion sequences, p. 109-162. In D.E. Berg and M.M. Howe (eds.), Mobile DNA. American society for Microbiology, Washington, D.C., USA
51 Xie, J., X. Wang, F. Li, Y. Peng, and G. Zhou. 2007. Three new loci of insertion element IS1112 in Chinese strains of Xanthomonas oryzae pv. oryzae. J. Microbiol. 45, 219-226   과학기술학회마을
52 Rajeshwari, R. and R.V. Sonti. 2001. Stationary-phase variation due to transposition of novel insertion elements in Xanthomonas oryzae pv. oryzae. J. Bacteriol. 82, 4797-4802
53 Thomas, L. and U. Bonus. 2001. Molecular secrets of bacterial type III effector protein. Trends Plant Sci. 6, 479-485   DOI   ScienceOn
54 Bonas, U. 1994. hrp Genes of phytopathogenic bacteria. Curr. Top. Microbiol. Immunol. 192, 79-98   PUBMED
55 Furutani, A., S. Tsuge, T. Oku, K. Tsuno, Y. Inoue, H. Ochiai, H. Kaku, and Y. Kubo. 2003. Hpal secretion via type III secretion system in Xanthomonas oryzae pv. oryzae. J. Gen. Plant Pathol. 69, 271-278   DOI
56 Yoon, K.H. and J.Y. Cho. 2007. Transcriptional analysis of the gum gene clusterfrom Xanthomonas oryzae pathovar oryzae. Biotechnol. Lett. 29, 95-103   DOI