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Changes in Coagulase Serotype of Staphylococcus aureus Isolates in Busan, 1994-2005  

Hwang, Soo-Myung (Department of Clinical Laboratory Science, Catholic University of Pusan)
Kim, Tae-Un (Department of Clinical Laboratory Science, Catholic University of Pusan)
Publication Information
Korean Journal of Microbiology / v.43, no.4, 2007 , pp. 346-350 More about this Journal
Abstract
We analyzed the phenotypic changes in coagulase serotype of S. aureus isolated from clinical sources and nasal cavities of healthy persons, $1994{\sim}2005$. A total of 715 isolates, 408 methicillin resistant S. aureus (MRSA) from clinical sources and 307 methicillin-susceptible S. aureus (MSSA), were classified into eight coagulase sero-types, I to VIII. The most prevalent serotype in MRSA was type II (54.3%, 222/408) and followed IV (24.7%), III (10.9%), and V (5.2%), whereas the majorities in MSSA were type VII (30.9%, 95/307), IV (22.2%), V (22.2%) and II (7.1%). Among the isolates collected periods, significant changes of coagulase serotypes in both strains were observed. In MRSA strains, the serotype V was not detected until 1997, but rapidly increased to 18.5% (20/108) in 2005, and the serotypes III decreased from 27% (31/115) in 1994 to 0.9% (1/108) in 2005. A similar trend in MSSA strains was observed but serotype II strain was not detected in 2005. The antigenic shift and changes in the coagulase of S. aureus were confirmed.
Keywords
coagulase serotyping; MRSA; Staphylococcus aureus;
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