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Biochemical Characteristics of Lrp (Leucine-responsive Regulatory Protein) as a Global Regulator in Escherichia coli  

Lee, Chan-Yong (Department of Biochemistry, Chungnam National University)
Kim, So-Young (Department of Biochemistry, Chungnam National University)
Kim, Ryu-Ryun (Department of Biochemistry, Chungnam National University)
Publication Information
Korean Journal of Microbiology / v.42, no.4, 2006 , pp. 239-245 More about this Journal
Abstract
Leucine-responsive Regulatory Protein (Lrp) is a global regulator involved in modulating a variety of metabolic functions, including the catabolism and anabolism of amino acids as well as pili synthesis. In addition, there is growing evidences that Lrp may play an important role when cells make transition between rich and lean nutritional conditions. In this review, the biochemical characteristics of Lrp are described to provide a good example that shows how bacteria adapt to nutrient limitation and environmental stress.
Keywords
amino acid metabolism; global regulator; Lrp; stationary phase;
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