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http://dx.doi.org/10.14474/ptrs.2021.10.3.343

Effects of Manual Therapy on Upper Extremity Pain after Breast Cancer Surgery: A Systematic Review and Meta-analysis  

Kim, Sangyeop (Department of Physical Therapy, Gwangju Health University)
Kim, Hyun-Joong (Cancer Center Chunghalin Hospital)
Publication Information
Physical Therapy Rehabilitation Science / v.10, no.3, 2021 , pp. 343-350 More about this Journal
Abstract
Objective: The most common type of cancer in women is breast cancer, and pain in the upper extremity and trunk is a discomfort experienced by more than half. Based on the evidence that manual therapy is effective for pain control in postoperative rehabilitation, this study aims to analyze the effects of manual therapy on upper extremity pain and function in patients after breast cancer surgery. Design: A systematic review and meta-analysis. Methods: We searched MEDLINE, Embase, PEDro, and CINAHL databases until August 2021. We included randomized controlled trial evaluating pain and function in patients after breast cancer surgery. Qualitative analysis was performed using Cochrane's risk of bias tool, and quantitative analysis was performed using RevMan 5.4 to analyze post-intervention outcomes. Results: Four randomized controlled trials were selected to evaluate the effects of upper extremity pain and function in 133 patients who underwent manual therapy after breast cancer surgery. In the results of qualitative and quantitative analysis, the experimental group treated with manual therapy showed a significant improvement in pain compared to the control group (-0.62; 95% confidence interval (CI) -0.97 to -0.27). However, there was no significant improvement in upper extremity function (-0.09; 95% CI -0.43 to 0.25). Conclusions: Current evidence shows that manual therapy is effective for pain control in patients who complain of upper extremity pain after breast cancer surgery.
Keywords
Breast cancer; Manual therapy; Postoperative pain; Cancer pain; Physical therapy;
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1 Lee PLT, Tam K-W, Yeh M-L, Wu W-W. Acupoint stimulation, massage therapy and expressive writing for breast cancer: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2016;27:87-101.   DOI
2 Eyigor S, Uslu R, Apaydin S, Caramat I, Yesil H. Can yoga have any effect on shoulder and arm pain and quality of life in patients with breast cancer? A randomized, controlled, single-blind trial. Complement Ther Clin Pract. 2018;32:40-5.   DOI
3 Stubblefield MD, Custodio CM. Upper-extremity pain disorders in breast cancer. Arch Phys Med Rehabil. 2006;87:96-9.   DOI
4 Runowicz CD, Leach CR, Henry NL, Henry KS, Mackey HT, Cowens-Alvarado RL, et al. American cancer society/American society of clinical oncology breast cancer survivorship care guideline. CA Cancer J Clin. 2016;66:43-73.   DOI
5 FERNANDEZ-LAO C, CANTARERO-VILLANUEVA I, DIAZ-RODRIGUEZ L, Cuesta-Vargas A, FERNANDEZ- DELAS-PENAS C, ARROYO-MORALES M. Attitudes towards massage modify effects of manual therapy in breast cancer survivors: a randomised clinical trial with crossover design. Eur J Cancer Care. 2012;21:233-41.   DOI
6 Basilio FB, Dos Anjos RdMM, De Medeiros EP, De Melo EMF, da Silva RMV. Effects of manual therapy techniques in the treatment of pain in post mastectomy patients: systematic review. Man Ther Posturol Rehabil J. 2014:1-6.
7 Riley RD, Higgins JP, Deeks JJ. Interpretation of random effects meta-analyses. BMJ. 2011;342:d549.   DOI
8 De Groef A, Van Kampen M, Vervloesem N, Dieltjens E, Christiaens M-R, Neven P, et al. Effect of myofascial techniques for treatment of persistent arm pain after breast cancer treatment: randomized controlled trial. Clin Rehabil. 2018;32:451-61.   DOI
9 Rangon FB, Ferreira VTK, Rezende MS, Apolinario A, Ferro AP, de Oliveira Guirro EC. Ischemic compression and kinesiotherapy on chronic myofascial pain in breast cancer survivors. J Bodyw Mov Ther. 2018;22:69-75.   DOI
10 Kehlet H. Acute pain control and accelerated postoperative surgical recovery. Surg Clin North Am. 1999;79:431-43.   DOI
11 Pollo A, Vighetti S, Rainero I, Benedetti F. Placebo analgesia and the heart. Pain. 2003;102:125-33.   DOI
12 Green S, Higgins JP. Cochrane handbook for systematic reviews of interventions version 5.1.0.: Cochrane Collaboration; 2011.
13 Price DD, Staud R, Robinson ME, Mauderli AP, Cannon R, Vierck CJ. Enhanced temporal summation of second pain and its central modulation in fibromyalgia patients. Pain. 2002;99:49-59.   DOI
14 Vernon H, Humphreys B. Manual therapy for neck pain: an overview of randomized clinical trias and systematic reviews. Europa Medicophysica. 2007;43:91.
15 Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics. 2000;56:455-63.   DOI
16 Wisotzky E, Hanrahan N, Lione TP, Maltser S. Deconstructing postmastectomy syndrome: implications for physiatric management. Phys Med Rehabil Clin N Am. 2017;28:153-69.   DOI
17 De Groef A, Van Kampen M, Dieltjens E, Christiaens M-R, Neven P, Geraerts I, et al. Effectiveness of postoperative physical therapy for upper-limb impairments after breast cancer treatment: a systematic review. Arch Phys Med Rehabil. 2015;96:1140-53.   DOI
18 Kim MH, Lee KY, Park S, Kim SI, Park HS, Yoo YC. Effects of systemic lidocaine versus magnesium administration on postoperative functional recovery and chronic pain in patients undergoing breast cancer surgery: a prospective, randomized, double-blind, comparative clinical trial. PloS one. 2017;12:e0173026.   DOI
19 Teguh DN, Raap RB, Struikmans H, Verhoef C, Koppert LB, Koole A, et al. Hyperbaric oxygen therapy for late radiation-induced tissue toxicity: prospectively patient-reported outcome measures in breast cancer patients. Radiat Oncol. 2016;11:1-6.   DOI
20 Cho Y, Do J, Jung S, Kwon O, Jeon JY. Effects of a physical therapy program combined with manual lymphatic drainage on shoulder function, quality of life, lymphedema incidence, and pain in breast cancer patients with axillary web syndrome following axillary dissection. Support Care Cancer. 2016;24:2047-57.   DOI
21 Goffaux P, Redmond WJ, Rainville P, Marchand S. Descending analgesia-when the spine echoes what the brain expects. Pain. 2007;130:137-43.   DOI
22 Serra-Ano P, Ingles M, Bou-Catala C, Iraola-Lliso A, Espi-Lopez GV. Effectiveness of myofascial release after breast cancer surgery in women under-going conservative surgery and radiotherapy: a randomized controlled trial. Support Care Cancer. 2019;27:2633-41.   DOI
23 Lanotte M, Lopiano L, Torre E, Bergamasco B, Colloca L, Benedetti F. Expectation enhances autonomic responses to stimulation of the human sub-thalamic limbic region. Brain Behav Immun. 2005;19:500-9.   DOI
24 Johansen O, Brox J, Flaten MA. Placebo and nocebo responses, cortisol, and circulating beta-endorphin. Psychosom Med. 2003;65:786-90.   DOI
25 da Silva FP, Moreira GM, Zomkowski K, de Noronha MA, Sperandio FF. Manual therapy as treatment for chronic musculoskeletal pain in female breast cancer survivors: a systematic review and meta-analysis. J Manipulative Physiol Ther. 2019;42:503-13.   DOI
26 Nijs J, Girbes EL, Lundberg M, Malfliet A, Sterling M. Exercise therapy for chronic musculoskeletal pain: innovation by altering pain memories. Man Ther. 2015;20:216-20.   DOI
27 Bialosky JE, Bishop MD, Price DD, Robinson ME, George SZJMt. The mechanisms of manual therapy in the treatment of musculoskeletal pain: a comprehensive model. Man Ther. 2009;14:531-8.   DOI