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The Ongoing Effect of Transcranial Direct Current Stimulation on both the Hemispheres: Single Case fMRI Study  

Kwon, Jung-Won (Department of Rehabilitation Science, Graduate School, Daegu University)
Son, Sung-Min (Department of Rehabilitation Science, Graduate School, Daegu University)
Kim, Chung-Sun (Department of Physical Therapy, College of Rehabilitation, Daegu University)
Cho, In-Sul (Department of Physical Therapy, Yeungnam College of Science and Technology)
Publication Information
The Journal of Korean Physical Therapy / v.23, no.6, 2011 , pp. 49-53 More about this Journal
Abstract
Purpose: The purpose of this study is to investigate whether dual-hemisphere transcranial direct current stimulation (tDCS) could induce more cortical activity, compared to single-hemisphere, using functional MRI (fMRI). Methods: One right-handed healthy subject was recruited. Three phases of dual-hemisphere tDCS (i.e. anodal tDCS over the left-dominant primary sensoriomotor cortex (SM1) and cathodal tDCS over the right-non dominant SM(1) were consecutively delivered on to a subject, during fMRI scanning. The voxel count and the intensity index in the averaged cortical map were analyzed among the three tDCS phases. Results: Our result showed that cortical activation was observed on all the three phases of the dual-hemisphere tDCS. Voxel count and intensity index were as following; 912 and 4.07 in the first phase, 1102 and 3.90 in the second phase, 1031 and 3.80 in the third phase. Conclusion: This study demonstrated that application of the dual-hemisphere tDCS could induce cortical activity and maintain to recruit cortical neurons. Our findings suggested that application of dual-hemisphere tDCS could produce efficiency of the ongoing tDCS effect to facilitate cortical excitability.
Keywords
Transcranial direct current stimulation; Dual-hemispheric stimulation; Cortical activation;
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