Browse > Article

Correlations of Physical Fitness Factors, Antioxidant Enzymes, Lipid Peroxidation, Lipid Profiles, Lactate Levels and Cardiovascular Variables in an Exercising Group and Controls  

Yu, Jae-Ho (Department of Physical Therapy, Graduate school of Sahmyook University)
Lee, Suk-Min (Department of Physical Therapy, Sahmyook University)
Publication Information
The Journal of Korean Physical Therapy / v.22, no.3, 2010 , pp. 61-69 More about this Journal
Abstract
Purpose: This study was designed to investigate correlations between physical fitness, antioxidant enzymes (SOD, CAT, GPX), lipid peroxidation levels (MDA), lipid profiles, lactate levels and cardiovascular variables in an exercising group and a control group. Methods: Twelve healthy young males (Exercise group: 6, Controls: 6). All subjects took physical fitness tests and blood samples were collected while subjects were resting. Results: In the exercise group, there were several significant correlations: between back strength and SOD enzyme levels (r=0.82, p=0.04), back strength and MDA (r=0.94, p=0.00), agility and GPX (r=0.81, p=0.04), and balance and GPX (r=0.81, p=0.04). In the control group, there were significant correlations between: dominant grip strength and MDA (r=-0.84, p=0.03), and agility and GPX (r= -0.82, p=0.04). In the exercise group, there were no significant correlations between physical fitness factors, TC, TG, HDL-C and lactate levels. In the control group, there were significant correlations between: back strength and TG (r=0.88, p=0.01), and agility and HDL-C (r= -0.84, p=0.03). In the exercise group, there were significant correlations between: non-dominant grip strength and SBP (r=0.94, p=0.00), dominant grip strength and SBP (r=0.85, p=0.03), and power and SBP (r=0.82, p=0.04). In controls, there were significant correlations between: dominant grip strength and DBP (r=-0.85, p=0.03), muscular endurance and ST level (r=-0.93, p=0.00), and muscular endurance and HR (r=-0.88, p=0.01). Conclusion: That cardiovascular patients and controls who participated in regular exercise maintained their antioxidant capacity suggests that long-term physical activity can counteract the negative dysfunction that characterizes sedentary lifestyle, probably by maintaining plasma antioxidant defenses and thereby preventing oxidative stress.
Keywords
SOD; CAT; GPX; Lactic acid; Short-term exercise;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Lee TS, Kim HH. The effect of physical function and quality of life in patient with amyotrophic lateral sclerosis through physical therapy and occupational therapy: a case study. J Kor Soc Phys Ther. 2007;19(5):77-85.   과학기술학회마을   DOI
2 Poyton RO, Ball KA, Castello PR. Mitochondrial generation of free radicals and hypoxic signaling. Trends Endocrinol Metab. 2009;20(7):332-40.   DOI   ScienceOn
3 Ji LL. Antioxidant enzyme response to exercise and aging. Med Sci Sports Exerc. 1993;25(2):225-31.
4 Finaud J, Degoutte F, Scislowski V et al. Competition and food restriction effects on oxidative stress in judo. Int J Sports Med. 2006;27(10):834-41.   DOI   ScienceOn
5 Powers SK, Jackson MJ. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev. 2008;88(4):1243-76.   DOI   ScienceOn
6 Banerjee AK, Mandal A, Chanda D et al. Oxidant, antioxidant and physical exercise. Mol Cell Biochem. 2003;253 (1-2):307-12.   DOI
7 Kraemer WJ, Bradley CN. Factors involved with overtraining for strength and power. In: Kreider RB et al, eds, Overtraining in sport, IL, Human Kinetics, 1998.
8 Kreider RB, Fry AC, O'Toole ML. Overtraining in sport. IL, Human Kinetics, 1998.
9 Ji LL. Exercise, oxydative stress, and antioxidants. Am J Sports Med. 1996;24(6 Suppl):S20-4.
10 Nzengue Y, Steiman R, Garrel C et al. Oxidative stress and DNA damage induced by cadmium in the human keratinocyte HaCaT cell line: role of glutathione in the resistance to cadmium. Toxicology. 2008;243(1-2):193-206.   DOI
11 Woo JH, Yeo NH, Kang SH. The effects of aerobic exercise program participation on antioxidant related gene expression and lipid, DNA damage in children with IDDM. Kor J Sports Sci. 2008;19(3):31-8.
12 Lee HJ, Song JY. The effect of passive movement on range of motion in temporomandibular joint. J Kor Soc Phys Ther. 2007;19(4):43-51.   과학기술학회마을
13 Ferdowsian HR, Barnard ND. Effects of plant-based diets on plasma lipids. Am J Cardiol. 2009;104(7):947-56.   DOI   ScienceOn
14 Shin HK, Cho KH. Association between physical performance and bone mineral density in elderly women. J Kor Soc Phys Ther. 2009;21(4):37-42.   과학기술학회마을   DOI
15 Morton JP, Kayani AC, McArdle A et al. The exercise-induced stress response of skeletal muscle, with specific emphasis on humans. Sports Med. 2009;39(8):643-62.   DOI   ScienceOn
16 Mensink RP, Zock PL, Kester AD et al. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a metaanalysis of 60 controlled trials. Am J Clin Nutr. 2003;77(5): 1146-55.
17 Jo HS. A study on effects and prescription of exercise for cardiac rehabilitation - coronary heart disease patients. Kor J Gachon gil college. 1998;(26):25-34.
18 Lee DS, Lee BH, Kim JK et al. The effects of aerobic exercise and weight training on changes of blood lipid profile in obese middle school student. Kor J Exer Sci. 2003;12(2):233-42.
19 Al-Sarraj T, Saadi H, Volek JS et al. Metabolic syndrome prevalence, dietary intake, and cardiovascular risk profile among overweight and obese adults 18-50 years old from the United Arab Emirates. Metab Syndr Relat Disord. 2010;8(1):39-46.   DOI   ScienceOn
20 Elsawy B, Higgins KE. Physical activity guidelines for older adults. Am Fam Physician. 2010;81(1):55-9.
21 Thompson PD, Cullinane E, Henderson LO et al. Acute effects of prolonged exercise on serum lipids. Metabolism. 1980;29(7):662-5.   DOI   ScienceOn
22 Jenkins RR. Free radical chemistry: relationship to exercise. Sports Med. 1988;5(3):156-70.   DOI   ScienceOn
23 Hunter JE, Zhang J, Kris-Etherton PM. Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids. Am J Clin Nutr. 2010;91(1): 46-63.   DOI   ScienceOn
24 Vincent HK, Powers SK, Stewart DJ et al. Short-term exercise training improves diaphragm antioxidant capacity and endurance. Eur J Appl Physiol. 2000;81(1-2):67-74.   DOI
25 Ko SE, Roh SK. The changes of MDA, SOD and GPX according to exercise intensity. Institute for Physical Education & Sports Science Kangweon National. 2001;(24):205-25.
26 Maso F, Lac G, Robert A et al. Lipids and theirs carriers in sportsmen: the lipoprotein particles. Eur J Appl Physiol. 2002;88(1-2):128-33.   DOI   ScienceOn
27 Ohno H, Sato Y, Tamashita K et al. The effect of brief physical exercise on free radical scavenging enzyme systems in human red blood cells. Can J Physiol Pharmacol. 1986; 64(9):1263-5.   DOI   ScienceOn
28 Ji LL, Fu R, Mitchell EW. Glutathione and antioxidant enzymes in skeletal muscle: effects of fiber type and exercise intensity. J Appl Physiol. 1992;73(5):1854-9.   DOI
29 Jee YS. Clinical exercise prescription. Seoul, 21 Century Education, 2004.
30 Reddy CP, Fernandes G. Modulation of antioxidant enzymes and lipid peroxidation in salivary gland and other tissues in mice by moderate treadmill exercise. Aging (Milano). 1999; 11(4):246-52.
31 Nikolaidis MG, Jamurtas AZ. Blood as a reactive species generator and redox status regulator during exercise. Arch Biochem Biophys. 2009;490(2):77-84.   DOI   ScienceOn
32 Carole MS, Carolyn AD, Susan DC. Exercise and cancer recovery. IL, Human Kinetics, 2003.
33 Amy H, Andrea L. Essential exercises for breast cancer survivor. Massachusetts, Havard common press, 2000.