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http://dx.doi.org/10.5657/kfas.2011.44.1.045

Tetramine Analysis using Liquid Chromatography-Tandem Mass Spectrometry and Ion Chromatography  

Song, Ki-Cheol (Food Safety Research Division, National Fisheries Research and Development Institute)
Lee, Ka-Jeong (Food Safety Research Division, National Fisheries Research and Development Institute)
Kim, Ji-Hoe (Food Safety Research Division, National Fisheries Research and Development Institute)
Yoon, Ho-Dong (Food Safety Research Division, National Fisheries Research and Development Institute)
Yu, Hong-Sik (Food Safety Research Division, National Fisheries Research and Development Institute)
Mok, Jong-Soo (Food Safety Research Division, National Fisheries Research and Development Institute)
Publication Information
Korean Journal of Fisheries and Aquatic Sciences / v.44, no.1, 2011 , pp. 45-49 More about this Journal
Abstract
As a first step toward identifying a new method for testing sea snail tissue for toxins, and thus prevent food poisoning due to the ingestion of contaminated snails, we measured the tetramine [$(CH_3)_4N^+$] contents of sea snails from the Korean coast using both liquid chromatography-tandem mass spectrometry (LC-MS/MS) and ion chromatography. For tetramine tested, good linearity ($r^2$ = 0.9996) was observed between the amounts in the injected samples and the peak areas of standard toxins, which ranged from 0.1 to 100 ng. The recovery (%) of tetramine from spiked tissue and mid-gut gland samples ranged from 84.0 to 95.3%. The quantitative results for tetramine using this method were in good agreement with the theoretical values. LC-MS/MS has both high sensitivity and selectivity, which makes it possible to measure trace quantities of tetramine in samples.
Keywords
Tetramine; LC-MS/MS; Ion chromatography; Sea snail;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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