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http://dx.doi.org/10.5657/kfas.2010.43.1.033

Antibacterial Activity of Bacillus sp. DH-9 Isolated from Sea Water  

Kim, Young-Man (Blue-Bio Industry RIC, Dongeui University)
Kim, Do-Kyun (Department of Life Science and Biotechnology)
Kim, Nam-Hee (Department of Life Science and Biotechnology)
Byun, Tae-Hwan (Department of Life Science and Biotechnology)
Kim, Ah-Ra (Department of Life Science and Biotechnology)
Lee, Eun-Woo (Department of Life Science and Biotechnology)
Kwon, Hyun-Ju (Department of Life Science and Biotechnology)
Kim, Byung-Woo (Department of Life Science and Biotechnology)
Publication Information
Korean Journal of Fisheries and Aquatic Sciences / v.43, no.1, 2010 , pp. 33-38 More about this Journal
Abstract
Emerging of antibiotic resistance of pathogenic bacteria is now a very serious problem in the clinics to treat the diseases, which have been easy to cure by antibiotic treatments before. Unfortunately, antibiotics developed till now are not effective any more against the resistant bacteria. Lots of efforts to discover new antibiotics having novel and unique structures and functions are really urgent and undergoing in the whole world. In this study, we tried to screen and isolate Same unique bacterial strains producing antibacterial substances from the sea water, which is the poor environment for bacteria 10 make their growing. Three bacterial strains among 916 strains isolated showed inhibition clear zone on the marine agar plate growing pathogenic bacteria including Acinetobacter baumannii, Edwardsiella tarda, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella enterica. One of them, which was identified as Bacillus sp. DH-9 from 16S rRNA gene analysis, showed especially considerable antibacterial activity against S. aureus which is notorious for methicillin resistant S. aureus (MRSA). The growth of S. aureus was totally inhibited when the supernatant of Bacillus sp. DH-9 culture was treated on.
Keywords
Antibacterial activity; Bacteria identification; Pathogenic bacteria; Staphylococcus aureus; Bacillus sp.;
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