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http://dx.doi.org/10.5657/kfas.2008.41.5.324

Trimethoprim Resistance of Vibrio parahaemolyticus Isolated from the Fish Farm  

Oh, Eun-Gyoung (Food Safety Research Team, NFRDI)
Yu, Hong-Sik (Food Safety Research Team, NFRDI)
Shin, Soon-Bum (Food Safety Research Team, NFRDI)
Son, Kwang-Tae (South Sea Research Institute, NFRDI)
Park, Kun-Bawui (South Sea Research Institute, NFRDI)
Kwon, Ji-Young (South Sea Research Institute, NFRDI)
Lee, Tae-Seek (Aquaculture Environment Research Center, NFRDI)
Lee, Hee-Jung (Food Safety Research Team, NFRDI)
Publication Information
Korean Journal of Fisheries and Aquatic Sciences / v.41, no.5, 2008 , pp. 324-329 More about this Journal
Abstract
Vibrio parahaemolyticus species, which cause acute gastroenteritis in humans, were isolated from farmed fish and seawater and their antimicrobial-resistance pattern and factor were investigated. They exhibited the highest resistance to ampicillin (88.9%), followed by trimethoprim (51.9%) and rifampin (22.2%). The relatively high resistance to trimethoprim was unexpected because trimethoprim was not commonly used in fish farming in Korea. R plasmid related resistance was identified by the treatment of novobiocin (7 ug/mL) and it was named as pVPBW1. A putative trimethoprim resistance gene in 2.0 kb fragment of pVPBW1 was also confirmed.
Keywords
Antimicrobial resistance; R plasmid; trimethoprim; Vibrio parahaemolyticus;
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