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http://dx.doi.org/10.15701/kcgs.2018.24.5.31

Automated Classification of Ground-glass Nodules using GGN-Net based on Intensity, Texture, and Shape-Enhanced Images in Chest CT Images  

Byun, So Hyun (Department of Software Convergence, Seoul Women's University)
Jung, Julip (Department of Software Convergence, Seoul Women's University)
Hong, Helen (Department of Software Convergence, Seoul Women's University)
Song, Yong Sub (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center)
Kim, Hyungjin (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center)
Park, Chang Min (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center)
Abstract
In this paper, we propose an automated method for the ground-glass nodule(GGN) classification using GGN-Net based on intensity, texture, and shape-enhanced images in chest CT images. First, we propose the utilization of image that enhances the intensity, texture, and shape information so that the input image includes the presence and size information of the solid component in GGN. Second, we propose GGN-Net which integrates and trains feature maps obtained from various input images through multiple convolution modules on the internal network. To evaluate the classification accuracy of the proposed method, we used 90 pure GGNs, 38 part-solid GGNs less than 5mm with solid component, and 23 part-solid GGNs larger than 5mm with solid component. To evaluate the effect of input image, various input image set is composed and classification results were compared. The results showed that the proposed method using the composition of intensity, texture and shape-enhanced images showed the best result with 82.75% accuracy.
Keywords
Chest CT image; Ground-glass Nodule; Nodule Classification; CNN;
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1 장승훈, 등., "폐결절," 대한내과학회지, 제 79 권 부록 2호, 2010.
2 C.I. Henschke, et al., "CT screening for lung cancer: frequency and significance of part-solid and non-solid nodules," Am.J.Roentgenol, Vol. 178, No. 5, pp. 1053-1057, 2002.   DOI
3 D.P. Naidich, et al., "Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society," Radiology, Vol266, No. 1, pp. 304-317, 2013.   DOI
4 H. MacMahon, et al, "Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017," Radiology, Vol.284, No.1, pp. 228-243, 2017.   DOI
5 M. Sergeeva, et al., "Classification of pulmonary nodules on computed tomography scans. Evaluation of the effectiveness of application of textural features extracted using wavelet transform of image," In Proveedings of the 18th Conference of Open Innovations Association FRUCT, pp. 291-299, 2016.
6 S.G. Armato, et al., "LUNGx Challenge for computerized lung nodule classification," Journal of Medical Imaging, vol. 3, no. 4, pp. 044506-044506, 2016.   DOI
7 D. Kumar, et al., "Lung nodule classification using deep features in CT images," In Computer and Robot vision(CRV), 2015 12th Conference on. IEEE, pp. 133-138, 2015.
8 S.Y. Lee, et al., "Classification of Ground-Glass Opacity Nodules with Small Solid Components using Multiview Images and Texture Analysis in Chest CT Images", Journal of Korea Multimedia Society, Vol.20, No.7, pp. 994-1003, 2017.   DOI
9 S.Y. Lee, et al., "Multi-class Classification of Ground-glass Nodules using 2.5-dimensional Multiview-based Features and Data Augmentation" KIISE Transactions on Computing Practices, Vol.24, No.10, pp. 527-533, 2018.   DOI
10 N. Tajbakhsh, et al., "Comparing two classes of end-to-end machine-learning models in lung nodule detection and classification: MTANNs vs. CNNs", Pattern recognition, Vol.63, pp. 476-486, 2017.   DOI
11 K. Liu, et al., "Multiview Convolutional Neural Networks for lung nodule classification," International Journal of Imaging Systems and Technology, Vol.27, No.1, pp. 12-22, 2017.   DOI
12 W. Shen, et al., "Multi-crop convolutional neural networks for lung nodule malignancy suspiciousness classification," Pattern Recognition, Vol.61, pp.663-673, 2017.   DOI
13 R. Dey, et al., "Diagnostic classification of lung nodules using 3D neural networks" In Biomedical Imaging (ISBI 2018), IEEE 15th International Symposium on, pp. 774-778, 2018.
14 B. Xu, et al., "Empirical Evaluation of Rectified Activations in Convolutional Network, arXiv preprint ArXiv:1505.00853.