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http://dx.doi.org/10.4163/jnh.2016.49.5.269

Dietary effect of green tea extract on hydration improvement and metabolism of free amino acid generation in epidermis of UV-irradiated hairless mice  

Choi, Sumin (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Shin, Jihye (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Lee, Bomin (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Cho, Yunhi (Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University)
Publication Information
Journal of Nutrition and Health / v.49, no.5, 2016 , pp. 269-276 More about this Journal
Abstract
Purpose: Ultraviolet (UV) irradiation decreases epidermal hydration, which is maintained by reduction of natural moisturizing factors (NMFs). Among various NMFs, free amino acids (AA) are major constituents generated by filaggrin degradation. This experiment was conducted to determine whether or not dietary supplementation of green tea extract (GTE) in UV-irradiated mice can improve epidermal levels of hydration, filaggrin, free AAs, and peptidylarginine deiminase-3 (PAD3) expression (an enzyme involved in filaggrin degradation). Methods: Hairless mice were fed a diet of 1% GTE for 10 weeks in parallel with UV irradiation (group UV+1%GTE). As controls, hairless mice were fed a control diet in parallel with (group UV+) or without (group UV-) UV irradiation. Results: In group UV+, epidermal levels of hydration and filaggrin were lower than those in group UV-; these levels increased in group UV+1% GTE to levels similar to group UV-. Epidermal levels of PAD3 and major AAs of NMF, alanine, glycine and serine were similar in groups UV- and UV+, whereas these levels highly increased in group UV+1% GTE. Conclusion: Dietary GTE improves epidermal hydration by filaggrin generation and degradation into AAs.
Keywords
green tea extract (GTE); filaggrin; peptidylarginine deiminase-3 (PAD3); natural moisturizing factor (NMF);
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1 Kim J, Lee Y, Cho Y. Effects of dietary royal jelly on epidermal generation of ceramides from acidic sphingomyelin and glucosylceramides in UV-irradiated hairless mice. Curr Top Nutraceutical Res 2012; 10(3/4): 151-164.
2 Khan SG, Katiyar SK, Agarwal R, Mukhtar H. Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention. Cancer Res 1992; 52(14): 4050-4052.
3 Min J, Lee Y, Han SM, Choi Y. Dietary effect of royal jelly supplementation on epidermal levels of hydration, filaggrins, free amino acids and the related enzyme expression in UV irradiated hairless mice. Korean J Nutr 2013; 46(2): 109-118.   DOI
4 Katiyar SK, Elmets CA. Green tea polyphenolic antioxidants and skin photoprotection (Review). Int J Oncol 2001; 18(6): 1307-1313.
5 Jackson JK, Zhao J, Wong W, Burt HM. The inhibition of collagenase induced degradation of collagen by the galloyl-containing polyphenols tannic acid, epigallocatechin gallate and epicatechin gallate. J Mater Sci Mater Med 2010; 21(5): 1435-1443.   DOI
6 Hsu S, Bollag WB, Lewis J, Huang Q, Singh B, Sharawy M, Yamamoto T, Schuster G. Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes. J Pharmacol Exp Ther 2003; 306(1): 29-34.   DOI
7 Kiss I, Chen S, Tramposch KM. The effect of high and low ultraviolet-B dose exposure on the degree of hairless mouse skin wrinkling. Photochem Photobiol 1991; 53(1): 109-112.   DOI
8 Takami S, Imai T, Hasumura M, Cho YM, Onose J, Hirose M. Evaluation of toxicity of green tea catechins with 90-day dietary administration to F344 rats. Food Chem Toxicol 2008; 46(6): 2224-2229.   DOI
9 Ginger RS, Blachford S, Rowland J, Rowson M, Harding CR. Filaggrin repeat number polymorphism is associated with a dry skin phenotype. Arch Dermatol Res 2005; 297(6): 235-241.   DOI
10 Lee B, Kim J, Hwang J, Cho Y. Dietary effect of green tea extract on epidermal levels of skin pH related factors, lactate dehydrogenase protein expression and activity in UV-irradiated hairless mice. J Nutr Health 2016; 49(2): 63-71.   DOI
11 Dale BA, Resing KA, Lonsdale-Eccles JD. Filaggrin: a keratin filament associated protein. Ann N Y Acad Sci 1985; 455: 330-342.   DOI
12 Kanno T, Kawada A, Yamanouchi J, Yosida-Noro C, Yoshiki A, Shiraiwa M, Kusakabe M, Manabe M, Tezuka T, Takahara H. Human peptidylarginine deiminase type III: molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin. J Invest Dermatol 2000; 115(5): 813-823.   DOI
13 Pearton DJ, Nirunsuksiri W, Rehemtulla A, Lewis SP, Presland RB, Dale BA. Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates. Exp Dermatol 2001; 10(3): 193-203.   DOI
14 Steinert PM, Cantieri JS, Teller DC, Lonsdale-Eccles JD, Dale BA. Characterization of a class of cationic proteins that specifically interact with intermediate filaments. Proc Natl Acad Sci U S A 1981; 78(7): 4097-4101.   DOI
15 Visscher M, Robinson M, Wickett R. Stratum corneum free amino acids following barrier perturbation and repair. Int J Cosmet Sci 2011; 33(1): 80-89.   DOI
16 Yamada Y, Obayashi M, Ishikawa T, Kiso Y, Ono Y, Yamashita K. Dietary tocotrienol reduces UVB-induced skin damage and sesamin enhances tocotrienol effects in hairless mice. J Nutr Sci Vitaminol (Tokyo) 2008; 54(2): 117-123.   DOI
17 Scott IR, Harding CR, Barrett JG. Histidine-rich protein of the keratohyalin granules. Source of the free amino acids, urocanic acid and pyrrolidone carboxylic acid in the stratum corneum. Biochim Biophys Acta 1982; 719(1): 110-117.   DOI
18 Kam E, Resing KA, Lim SK, Dale BA. Identification of rat epidermal profilaggrin phosphatase as a member of the protein phosphatase 2A family. J Cell Sci 1993; 106(Pt 1): 219-226.
19 Jiang SJ, Chu AW, Lu ZF, Pan MH, Che DF, Zhou XJ. Ultraviolet B-induced alterations of the skin barrier and epidermal calcium gradient. Exp Dermatol 2007; 16(12): 985-992.   DOI
20 Jang SI, Steinert PM, Markova NG. Activator protein 1 activity is involved in the regulation of the cell type-specific expression from the proximal promoter of the human profilaggrin gene. J Biol Chem 1996; 271(39): 24105-24114.   DOI
21 Balasubramanian S, Efimova T, Eckert RL. Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes. J Biol Chem 2002; 277(3): 1828-1836.   DOI
22 Koyama J, Horii I, Kawasaki K, Nakayama Y, Morikawa Y, Mitsui T, Kumagai H. Free amino acids of stratum corneum as a biochemical marker to evaluate dry skin. J Soc Cosmet Chem 1984; 35(4): 183-195.
23 Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W. Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol 2011; 131(11): 2233-2241.   DOI
24 Kim Y, Han SM, Cho Y. The dietary effect of royal jelly supplementation on epidermal levels of filaggrin and free amino acids during menopause in rats. J Korean Soc Food Sci Nutr 2013; 42(3): 389-396.   DOI
25 Hsu S, Yamamoto T, Borke J, Walsh DS, Singh B, Rao S, Takaaki K, Nah-Do N, Lapp C, Lapp D, Foster E, Bollag WB, Lewis J, Wataha J, Osaki T, Schuster G. Green tea polyphenol-induced epidermal keratinocyte differentiation is associated with coordinated expression of p57/KIP2 and caspase 14. J Pharmacol Exp Ther 2005; 312(3): 884-890.   DOI
26 Tabachnick J, LaBadie JH. Studies on the biochemistry of epidermis. IV. The free amino acids, ammonia, urea, and pyrrolidone carboxylic acid content of conventional and germ-free albino guina pig epidermia. J Invest Dermatol 1970; 54(1): 24-31.   DOI
27 Joo KM, Han JY, Son ED, Nam GW, Jeong HJ, Lim KM, Cho JC. Study on the relationship between skin dryness and amino acids in stratum corneum. J Soc Cosmet Sci Korea 2012; 38(1): 75-82.   DOI
28 Bak H, Hong SP, Jeong SK, Choi EH, Lee SE, Lee SH, Ahn SK. Altered epidermal lipid layers induced by long-term exposure to suberythemal-dose ultraviolet. Int J Dermatol 2011; 50(7): 832-837.   DOI
29 Kezic S, Kammeyer A, Calkoen F, Fluhr JW, Bos JD. Natural moisturizing factor components in the stratum corneum as biomarkers of filaggrin genotype: evaluation of minimally invasive methods. Br J Dermatol 2009; 161(5): 1098-1104.   DOI
30 Kim H, Oh I, Park KH, Kim NM, Do JH, Cho Y. Stimulatory effect of dietary red ginseng on epidermal hydration and ceramide levels in ultraviolet-irradiated hairless mice. J Med Food 2009; 12(4): 746-754.   DOI
31 Mark H, Harding CR. Amino acid composition, including key derivatives of eccrine sweat: potential biomarkers of certain atopic skin conditions. Int J Cosmet Sci 2013; 35(2): 163-168.   DOI
32 Tagami H. Functional characteristics of the stratum corneum in photoaged skin in comparison with those found in intrinsic aging. Arch Dermatol Res 2008; 300 Suppl 1: S1-S6.
33 Rawlings AV, Harding CR. Moisturization and skin barrier function. Dermatol Ther 2004; 17 Suppl 1: 43-48.   DOI
34 Baroni A, Buommino E, De Gregorio V, Ruocco E, Ruocco V, Wolf R. Structure and function of the epidermis related to barrier properties. Clin Dermatol 2012; 30(3): 257-262.   DOI
35 Verdier-Sevrain S, Bont F. Skin hydration: a review on its molecular mechanisms. J Cosmet Dermatol 2007; 6(2): 75-82.   DOI
36 Sandilands A, Sutherland C, Irvine AD, McLean WH. Filaggrin in the frontline: role in skin barrier function and disease. J Cell Sci 2009; 122(Pt 9): 1285-1294.   DOI
37 Nachat R, Méchin MC, Takahara H, Chavanas S, Charveron M, Serre G, Simon M. Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin. J Invest Dermatol 2005; 124(2): 384-393.   DOI
38 Gilchrest BA. Skin aging and photoaging: an overview. J Am Acad Dermatol 1989; 21(3 Pt 2): 610-613.   DOI
39 Chung JH. Photoaging in Asians. Photodermatol Photoimmunol Photomed 2003; 19(3): 109-121.   DOI
40 Gruber JV, Holtz R. Examining communication between ultraviolet (UV)-damaged cutaneous nerve cells and epidermal keratinocytes in vitro. Toxicol Ind Health 2009; 25(4-5): 225-230.   DOI
41 Hwang E, Sun ZW, Lee TH, Shin HS, Park SY, Lee DG, Cho BG, Sohn H, Kwon OW, Kim SY, Yi TH. Enzyme-processed Korean Red Ginseng extracts protects against skin damage induced by UVB irradiation in hairless mice. J Ginseng Res 2013; 37(4): 425-434.   DOI