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http://dx.doi.org/10.4163/jnh.2014.47.3.176

Relationship between flavonoids intake and metabolic syndrome in Korean women with polycystic ovary syndrome  

Oh, Ji Soo (Department of Nutritional Science and Food Management, Ewha Womans University)
Ahn, Mi Jin (Department of Nutritional Science and Food Management, Ewha Womans University)
Han, Chan Jung (Department of Nutritional Science and Food Management, Ewha Womans University)
Kim, Hyesook (Department of Nutritional Science and Food Management, Ewha Womans University)
Kwon, Oran (Department of Nutritional Science and Food Management, Ewha Womans University)
Chung, Hye Won (Department of Obstetrics and Gynecology, Ewha Womans University College of Medicine)
Chang, Namsoo (Department of Nutritional Science and Food Management, Ewha Womans University)
Publication Information
Journal of Nutrition and Health / v.47, no.3, 2014 , pp. 176-185 More about this Journal
Abstract
Purpose: The purpose of this study was to investigate the relationship between dietary flavonoids intake and metabolic syndrome (MetS) in Korean women with polycystic ovary syndrome (PCOS). Methods: A total of 223 subjects (mean age; $27.3{\pm}4.2$ yrs, range; 17-38 yrs) were divided into the MetS group (n = 27) and non-MetS group (n = 196). Dietary intake data were assessed by 24-hour recall method for two non-consecutive days and the average of the two days was used to estimate the usual dietary intake. Dietary habits were assessed using the Mini Dietary Assessment (MDA) score. We analyzed the intakes of six flavonoid classes (anthocyanidins, flavan-3-ols, flavanones, flavones, flavonols, and iso-flavones) using a flavonoids database. Results: After adjustment for age, total energy intake, alcohol consumption, smoking, regular exercise, and oral contraceptive use, dietary flavonols intake was significantly lower in the MetS group ($5.1{\pm}2.4$ mg/d) than in the non-MetS group ($8.9{\pm}2.8$ mg/d) (p = 0.0472). Intakes of other flavonoids except for flavonols did not differ between the two groups. In MDA scores, significant differences were observed only for that related to daily consumption of fruit or fruit juice (p = 0.0180). A significant inverse relationship was observed between flavonols intake and the risk of MetS (4th vs. 1st quartile, OR = 0.11, 95% CI = 0.02-0.62, p for trend = 0.0131). Conclusion: These results suggest that higher intake of flavonols may be beneficial for MetS in PCOS women.
Keywords
PCOS; metabolic syndrome; dietary flavonoids intake;
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