Browse > Article

Effects of Salicornia herbacea L. Supplementation on Lipid Peroxidation and Mineral Levels in Streptozotocin-Induced Diabetic Rats  

Kim, Myung-Wha (Department of Food and Nutrition, Duksung Women's University)
Publication Information
Journal of Nutrition and Health / v.40, no.5, 2007 , pp. 403-412 More about this Journal
Abstract
This study was designed to examine the effects of Salicornia herbacea L. (glasswort: GW) on the lipid peroxidation and mineral levels in diabetic rats. Diabetes mellitus was induced in male Sprague-Dawley rats weighing 200-220 g by an injection of streptozotocin (STZ) dissolved in a citrate buffer into the tail vein at a dose of 45 mg/kg of body weight. Sprague-Dawley rats were fed an AIN-93 recommended diet and the experimental groups were fed a modified diet containing 10% and 20% of glasswort powder for 4 weeks. The experimental groups were divided into 6 groups which consisted of normal (N)-control group, N-GW 10% and N-GW 20% treated groups, STZ-control, STZ-GW 10% and STZ-GW 20% treated groups. The rats' liver and muscle glycogen, liver and kidney protein, cholesterol and triglyceride (TG) in liver, malondialdehyde (MDA) in liver and kidney values were measured, along with the hepatic of chromium (Cr), iron (Fe), and zinc (Zn) content. The liver glycogen levels was significantly affected in N-GW 20% group among all the experimental groups. The liver MDA levels of the STZ-GW 10% and STZ-GW 20% groups were significantly lower than for the STZ-control group. There were significant differences between the N-control group and the STZ-control group in the hepatic of Zn levels. The hepatic of Cr levels in the N-GW 20% and STZ-GW 10% and STZ-GW 20% groups were significanly higher than for the each control groups. These results exhibited dose related effect of glasswort and it may have favorable influence on lipid peroxidation in the liver.
Keywords
Salicornia herbacea L; streptozotocin; lipid peroxidation; mineral levels;
Citations & Related Records
Times Cited By KSCI : 11  (Citation Analysis)
연도 인용수 순위
1 Nikika EA, Kekki M. Plasma triglyceride transport kinetics in diabetes mellitus. Metabolism 1973; 22(1): 1-22   DOI   ScienceOn
2 Goswamy S, Mani I, Mani UV. Effects of wheat bran on tissue lipids in diabetic rats. Indian J Biochem Biophys 1985; 22(4): 240-243
3 Min JG, Son KT, Kim JH, Kim TJ, Park JH. Physiological and functional properties of Salicornia herbacea (Tungtungmadi) leaf extracts. J Food Sci Nutr 2002; 7(3): 261-264
4 Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998; 17(6): 548-555   DOI
5 Ahn YM, Lim SJ, Han HY, Choi SS. Effects of allium vegetable intake on levels of plasma glucose, lipid and minerals in streptozotocin induced diabetic rats. Korean J Nutr 2006; 39(5): 433- 443   과학기술학회마을
6 Anderson RA, Roussel AM, Zouari N, Mahjoub S, Matheau JM, Kerkeni A. Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus. J Am Coll Nutr 2001; 20(3): 212-218   DOI
7 Johnson WT, Evans GW. Effects of the interrelationship between dietary protein and minerals on tissue content of trace metals in streptozotocin-diabetic rats. J Nutr 1984; 114(1): 180-190   DOI
8 Korea statistical information system, Korea statistical year book, Seoul; 2005
9 Kannel WB, McGee DL. Diabetes and cardiovascular disease. JAMA 1979; 241(19): 2035-2038   DOI   ScienceOn
10 Mullarkey CJ, Edelstein D, Brownlee M. Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes. Biochem Biophys Res Commun 1990; 173(3): 932-939   DOI   ScienceOn
11 Bailey CJ, Day C. Traditional plant medicines as treatments for diabetes. Diabetes Care 1989; 12(8): 553-564   DOI   ScienceOn
12 Shin KS, Boo HO, Jeon MW, Ko JY. Chemical components of native plant, Salicornia herbacea L.. Korean J Plant Res 2002; 15(3): 216-220
13 El SN, Karakaya S. Radical scavenging and iron-chelating activities of some greens used as traditional dishes in Mediterranean diet. Int J Food Sci Nutr 2004; 55(1): 67-74   DOI   ScienceOn
14 Jang MS, Park JE. Optimization of ingredient mixing ratio for preparation of sulgidduk with saltwort (Salicornia herbacea L.). J Korean Soc Food Sci Nutr 2006; 35(5): 641-648   과학기술학회마을   DOI
15 Kim SK, Kim YC. The effect of repeated betaine treatment on hepatotoxicity and cytochrome P-450 dependent drug metabolism enzyme system. Yakhak Hoeji 1996; 40(4): 449-455
16 Kim MW. Effects of Salicornia herbacea L. supplementation on blood glucose and lipid metabolites in streptozotocin-induced diabetic rats. Korean J Nutr 2007; 40(1): 5-13   과학기술학회마을
17 Reeves PG. Components of the AIN-93 diets as improvements in the AIN-76A diet. J Nutr 1997; 127(5 Suppl): 838S-841S
18 Choi JK. A edible Korean medicinal herbs. J Korean Soc Plants People Environ 2002; 5(1): 7-19
19 Junod A, Lambert AE, Orci L, Pictet R, Gonet AE, Renold AE. Studies of the diabetogenic action of streptozotocin. Proc Soc Exp Biol Med 1967; 126(1): 201-205
20 Samson M, Fehlmann M, Dolais-Kitabgi J, Freychet P. Amino acid transport in isolated hepatocytes from streptozotocin diabetic rats. Diabetes 1980; 29(2): 996-1000   DOI   ScienceOn
21 Giegel JL, Ham AB, Clema W. Manual and semi-automated procedures for measurements of triglycerides in serum. Clin Chem 1975; 21(11): 1575-1581
22 Kamalakkanan N, Rajadurai M, Prince PS. Effect of aegle marmelos fruits on normal and streptozotocin-diabetic wistar rats. J Medicinal Food 2003; 6(2): 93-98   DOI   ScienceOn
23 Im JS, Lee SK, Chang IY, Ha HC, Lim Y, Kim HY, Park KH, Yoon SP. Activation of macrophage by polysaccharide isolated from Salicornia herbacea L.. Korean J Phys Anthropol 2006; 19(2): 117-124   DOI
24 Lee CH, Kim IH, Kim YE, Oh SW, Lee HJ. Determination of betaine from Salicornia herbacea L.. J Korean Soc Food Sci Nutr 2004; 33(9): 1584-1587   DOI
25 Meglasson MD, Burch PT, Berner DK, Najafi H, Matschinsky FM. Identifycation of glucokinase as an alloxan-sensitive glucose sensor of the pancreatic beta-cell. Diabetes 1986; 35(10): 1163- 1173   DOI   ScienceOn
26 Goldberg RB. Lipid disorders in diabetes. Diabets Care 1981; 4(5): 561-572   DOI   ScienceOn
27 Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem 1974; 20 (4): 470-475
28 Hribal ML, Oriente F, Accili D. Mouse models of insulin resistance. Am J Physiol Endocrinol Metab 2002; 282(5): E977-E981
29 Kim HJ, Bae KH, Lee HJ, Eun JB, Kim MK. Effect of hesperidin extracted from tangerine peel on Cd and lipid metabolism and antioxidant capacity in rats. Korean J Nutr 1999; 32(3): 137-149
30 Behrens WA, Madere R. Vitamin C and vitamin E status in the spontaneously diabetes BB rat before the onset of diabetes. Metabolism 1991; 40(1): 72-76   DOI   ScienceOn
31 Choi JW, Sohn KH, Kim SH. Effects of nicotinamide on the serum lipid composition in streptozotocin-induced diabetic rats. J Korean Soc Food Nutr 1991; 20(4): 306-311
32 Rhee SJ, Choe WK, Cha BK, Yang JA, Kim KY. Effects of vitamin E and selenium on the antioxidative defense system in streptozotocin- induced diabetic rats. J Medicinal Food 1996; 29(1) : 22-31
33 Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193 (1): 265-275
34 Alba-Loureiro TC, Hirabara SM, Mendonca JR, Curi R, Pithon- Curi TC. Diabetes causes marked changes in function and metabolism of rat neutrophils. J Endocrinol 2006; 188(2): 295-303   DOI   ScienceOn
35 Kim KR, Choi JH, Lee SK, Woo MH, Choi SW. Effect of enzymatic hydrolysate of Hamcho (Salosornia herbacea) on antioxidative defense system in rats fed high cholesterol diet. J Korean Soc Food Sci Nutr 2006; 35(10): 1356-1362   과학기술학회마을   DOI
36 Junod A, Lambert AE, Stauffacher W, Renold AE. Diabetogenic action of streptozotocin: relationship of dose to metabolic response. J Clin Invest 1969; 48(11): 2129-2139   DOI
37 Kim YS, Chun JH, Park JH, Kang CI. Status and associating factors of complementary and alternative medicine among Korean diabetic patients. J Kor Diabetes Assoc 2000; 24(1): 78-89
38 Han SK, Kim SM. Antioxidative effect of Salicornia herbacea L. grown in closed sea beach. J Korean Soc Food Sci Nutr 2003; 32(2): 207-210   DOI
39 Song TC, Lee CH, Kim YE, Kim IH, Han DS, Yang DH. The functionality of the saltwort (Salicornia herbacea L.) extract fermented juice. J Korean Soc Food Sci Nutr 2007; 36(4): 395-399   과학기술학회마을   DOI
40 Zimmet P, Alberti KGMM, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001; 414(6865) : 782-787   DOI   ScienceOn
41 Lee SZ. Changes in plasma lipid pattern in streptozotocin-induced diabetic rats: A time course study. Korean J Nutr 1999; 32(7): 767-774
42 Wolff SP, Dean RT. Glucose autoxidation and protein modification. The potential role 'autoxidative glycosylation' in diabetes. Biochem J 1987; 245(1): 243-250   DOI
43 Morgan JM. Hepatic chromium content of diabetic subjects. Metabolism 1972; 21(4): 313-320   DOI   ScienceOn
44 Abrams JJ, Ginsberg H, Grundy SM. Metabolism of cholesterol and plasma triglycerides in non-ketoic diabetes mellitus. Diabetes 1982; 31(10): 903-910   DOI   ScienceOn
45 Lee JT, An BJ. Detection of physical activity of Salicornia herbacea. Kor J Herbology 2002; 17(2): 61-69
46 Song YS, Yang JL, Suh MJ. Effect of sodium alginate and cellulose on gastrointestinal physiology in fats. J Kor Soc Food Sci Nutr 1996; 25(4): 551-559
47 Karpen CW, Cataland S, O'Dorisio TM, Panganamala RV. Produciton of 12-hydroxyeicosatetraenoic acid vitamin E status in platelets from type 1 human diabetic subjects. Diabetes 1985; 34(6): 526-531   DOI   ScienceOn
48 Park YM, Sohn CM, Jang HC. A study on subjective recognition of functional foods among diabetic patients. J Korean Dietetic Assoc 2005; 11(2): 216-222
49 Mihara M, Uchiyama M. Determination of malondialdehyde precursor in tissue by thiobarbituric acid test. Anal Biochem 1978; 86(1): 271-278   DOI   ScienceOn
50 Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27(5): 1047-1053   DOI   ScienceOn
51 Park SH, Kim KS. Isolation and identification of antioxidant flavonoids from Salicornia herbacea L.. J Korean Soc Appl Biol Chem 2004; 47(1): 120-123
52 Lee KW, Hong SB, Min KY, Lee SY, Nam MS, Kim YS, Ahn CW, Cha BS, Kim KR, Lee HC, Lee KW, Park TS. Resurvey of alternative medicine in korean type 2 diabetes mellitus after 10 years. J Kor Diabetes Assoc 2005; 29(3): 231-238
53 Shay G. Saline agriculture: Salt-tolerant plants for developing countries. Washington: National academy press; 1990. p.143
54 Min JG, Lee DS, Kim TJ, Park JH. Chemical composition of Salicornia herbacea L.. J Food Sci Nutr 2002; 7(1): 105-107   DOI
55 West KM, Ahuja MM, Bennett PH, Czzyk A, Acostea OMD, Fuller JH, Grab B, Grabauskas V, Jarrett RJ, Kosaka K, et al. The role of circulating glucose and triglyceride concentrations and their interactions with other risk factors as determinants of arterial disease in nine diabetic population samples from WHO multinational study. Diabetes Care 1983; 6(4): 361-369   DOI   ScienceOn
56 Wilson GL. Mechanism of streptozotocin-induced and alloxaninduced damage in rat ${\beta}-cells$. Diabetologia 1984; 27(6): 587-591   DOI   ScienceOn
57 Pritchard KA, Patel ST, Karper CW, Newman HA, Panganamala RV. Triglyceride-lowering effects of dietary vitamin E in streptozotocin induced diabeitc rats fed high vitamin E. Diabetes 1986; 35(3): 278-281   DOI   ScienceOn
58 Masataka Y, Keiko M. Interaction of iron with polyphenolic compounds: application to antioxidant characterization. Anal Biochem 1998; 257(1): 40-44   DOI   ScienceOn
59 Gregor A, Kostrzewska E, Godorowska W. Determination of serum proteins in the presence of dextran by means of the biuret reaction. Infusionsther Klin Ernahr 1977; 4(1): 48-50
60 Hassid WZ, Abraham X. Chemical procedures for analysis of polysaccharides in: Methods in Enzymology 3. Academic press; 1957. p.34-50
61 Cha JY, Jeong JJ, Kim YT, Seo WS, Yang HJ, Kim JS, Lee YS. Detection of chemical characteristics in hamcho (Salicornia herbacea L.) according to harvest periods. J Life Sci 2006; 16(4): 683-690   과학기술학회마을   DOI
62 Wolf HP, Engel DW. Decrease of fatty acid oxidation, ketogenesis and gluconeogenesis in isolated perfused rat liver phenylalkyl oxirane carbohydrate (B 807-27) due to inhibition of CPTI (EC 2.3.1.21). Eur J Biochem 1985; 146(2): 359-363   DOI   ScienceOn
63 Liu SM, Barac-Nieto M. Renal protein degradation in streptozotocin diabetic mice. Diabetes Res ＆ Clin Pract 1997; 34(3): 143-148   DOI   ScienceOn
64 Jo YC, Ahn JH, Chon SM, Lee KS, Bae TJ, Kang SK. Studies of pharmacological effects of glasswort (Salicornia herbacea L.). Korean J Medicinal Crop Sci 2002; 10(2): 93-99
65 Tamborlane WV, Sherwin RS, Genel M, Felig P. Restoration of normal lipid and aminoacid metabolism in diabetic patients treated with a portable insulin-infusion pump. Lancet 1979; 1(8129): 1258-1261
66 Lombardo YB, Serdikoff C, Thamotharan M, Paul HS, Adibi SA. Inverse alterations of BCKA dehydrogenase activity in cardiac and skeletal muscles of diabetic rats. Am J Physiol 1999; 277 (4pt1): E685-E692