Browse > Article

Effect of Dried Powders of Chamomile, Sage, and Green Tea on Antioxidative Capacity in 15-Month-Old Rats  

정세원 (이화여자대학교 식품영양학과)
김미경 (이화여자대학교 식품영양학과)
Publication Information
Journal of Nutrition and Health / v.36, no.7, 2003 , pp. 699-710 More about this Journal
Abstract
This study was performed to investigate the effect of chamomile, sage, and green tea intakes on anti oxidative capacity in 15-month-old rats. Dried powders of three plants were analyzed to determine the amount of total flavonoids, $\beta$-carotene, vitamin C, vitamin E, and dietary fibers. In order to examine the change of antioxidative capacity in old rats, forty-eight Sprague-Dawley male rats weighing 621.2$\pm$9.5 g were divided into four groups according to body weight and fed for four weeks with each experimental diet of three dried powders and control diet. Plasma and liver thiobarbituric acid reactive substances (TBARS) levels and xanthine oxidase (XO) activities, erythrocyte and liver superoxide dismutase (SOD) activities and plasma vitamin A, C, E, and total carotenoids levels were measured. The total flavonoids and vitamin C contents were the highest in green tea powder. Beta-carotene and vitamin E contents were not significantly different among all three dried powders. Total dietary fiber contents also were not different among all three dried powders, but soluble dietary fiber contents of chamomile was higher than other two dried powders. Plasma TBARS level was found to be significantly lower in all the experimental groups as compared to control group. Chamomile powder group, especially, showed the lowest level among all experimental groups. Liver TBARS levels of experimental groups were also lower than that of control group and significant differences were observed in chamomile and green tea groups compared to control. Plasma XO activity of green tea group was significantly lower than control group. Liver XO activities of green tea and chamomile groups were significantly lower than control group. Erythrocyte SOD activity was not significantly different among all the groups. However, liver SOD activities of sage and green tea groups showed a significant increase as compared to control group. Plasma vitamin A level was not significantly different among all the groups. Plasma total carotenoids levels were found to be significantly higher in experimental groups as compared to control group. Plasma vitamin E level of chamomile group and vitamin C level of green tea group showed the highest level among all the groups. In conclusion, chamomile, sage, and green tea intakes had an effect on improving antioxidative capacity in 15-month-old rats. Effects of green tea and chamomile powders, especially, were higher than sage powder.
Keywords
chamomile; sage; green tea; antioxidative capacity;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
연도 인용수 순위
1 Slater TF. Free-radical mechanisms in tissue injury. Biochem J 222: 1, 1984
2 Kang YH, Park YK, Ha TY and Moon KD. Effects of Pine Needle Extracts on Serum and Liver Lipid Contents in Rats Fed High Fat Diet. J Korean Soc Food Nutr 25 (3) : 367-373, 1996   DOI   ScienceOn
3 Dreosti IE,. Bioactive ingredients: antioxidants and polyphenols in tea. Nutr Rev 54: S51-58, 1996
4 Effect of Heat-treated Ceruloplasmin on the Hepatic Xanthine Oxidase Activity and Type Conversion /
[ Huh,K,;Shin,U.S.;Lee,S.I. ] / Arch Pharm Res   과학기술학회마을   DOI
5 Serum Levels of vitamin A and carotenoids as reflectors of nutritional status /
[ Olson,J.A. ] / J Natl Cancer Inst
6 Convenient assays for superoxide dismutase /
[ Flohe,L.;Becker,R.;Brigelius,R.;Lengfelder,E.;Otting,F. ] / CRC Handbook of Free Radicals and Antioxidants in Biomedicine
7 Flavonoids:Diet and Health Relationships /
[ Prior,R.L.;Cao,G. ] / Nutrition in Clinical Care   DOI   ScienceOn
8 A modified colorimetric assay for xanthine oxidase in rat liver extracts /
[ Yoon,C.G. ] / Keimyung Research Journal(Keimyung Junior College)
9 Vitamin E and vitamin C and carotenoids as antioxidants /
[ Sies,H.Stahlwilhelm. ] / Am j Clin Nutr
10 Antioxidants/antimutagens in food /
[ Namiki M. ] / Critical Reviews in Food Sci & Nutrition   DOI   ScienceOn
11 Antioxidant Activity and Phenolic Compounds in Selected Herbs /
[ Zheng,W.;Wang,S.Y. ] / J Agric Food Chem   DOI   ScienceOn
12 /
[ Korean National Statistical Office ] / Population Projections for Korea.2000-2050
13 Flavonoids inhibit the oxidative modification of low density lipoproteins by macrophages /
[ De,Whalley,C.V;Rankin,S.M.;Hoult,J.R.S.;Jessup,W.;Leake,D.S. ] / Biochem Pharmacol   DOI   ScienceOn
14 AIN-93 purified diets for laboratory rodents:final report of the American Institute Nutrition Ad Hoc Wrighting Commitee on the reformulation of the AIN76A rodent diet /
[ Reeves,P.G.;Nielsen,F.H.;Fahey,G.C. ] / J Nutr
15 Inhibitory Effect of Condensed Tannins Isolated from Korean Green Tea against Xanthine Oxidase /
[ Cho,Y.J.;Chun,S.S.;Choi,C.i. ] / J Korean Soc Food Nutr   과학기술학회마을
16 Effect of Dietary Polysaturated/Saturated Fatty Acid Ratio and Dietary Vitamin E on Lipid Peroxidation in the Rat /
[ Buckingham,K.W. ] / J Nutr
17 (+)-epi- -bisabolol is the woundhealing principle of Peperomia galioides:investigation of the in vivo wound-healing activity of related terpenoids /
[ Villegas,L.F.;Marcalo,A.;Martin,J.;Fernadez,I.D.;Maldonado,H.;Vaisberg,A.J.;Hammond,G.B. ] / J Nat Prod   DOI   ScienceOn
18 Antimutagenic effects and isolation of flavonoids from humulus japonicus extracts /
[ Park,S.W.;Kim,S.H.;Chung,S.K. ] / Korean J Food Sci Technol
19 Effects of Pine Needle Extracts on Serum and Liver Lipid Contents in Rats Fed High Fat Diet /
[ Kang,Y.H.;Park,Y.K.;Ha,T.Y.;Moon,K.D. ] / J Korean Soc Nutr
20 Contents of Total Flavonoid and Biological Activities of Edible Plants /
[ Lee,J.M;Son,E.S.;Oh,S.S.;Han,D.S. ] / Korean J Dietary Culture
21 Inhibition of cow's milk xanthine oxidase by flavonoids /
[ Hayashi,T.;Sawa,K.;kawasaki,M.;Arisawa,M.;Shimizu,M.;Morita,M. ] / J Natural Products   DOI
22 Inhibitory effects of galloylated flavonoids on xanthine oxidase /
[ Hatano,T.;Yasuhara,T.;Yoshihara,R.;Okuda,T. ] / Plant Med   DOI   ScienceOn
23 Carotenoid composition and antioxidant potential in subfractions of human low-density lipoprotein /
[ Lowe,G.M.;Bilton,R.F.;Davies,I.G.;Ford,T.C.;Billington,D.;Young,A.J. ] / Ann Clin Biochem
24 Role of vitamin E in preventing the oxidation of low-density lipoprotein /
[ Esterbauer,H.;Dieber-Rotheneder,M.;Striegl,G.;Waeg,G. ] / Am J Clin Nutr
25 Effects of Pine Needle Extracts on Enzymetic Activities of Serum and Liver, and Liver Morphology in Rats Fed High Fat Diet /
[ Knag,Y.H.;Park,Y.K.;Ha,T.Y.;Moon,K.D. ] / J Korean Soc Food Nutr   과학기술학회마을
26 Measurement of Xanthine Oxidase in Biological Tissues /
[ Terada,L.S.;Leff,A. ] / Methods in enzymology   DOI
27 Antioxidant activity and total phenolics in seletced fruits,vegetables,and grain products /
[ Velioglu,Y.S.;Mazza,G.;Gao,L.;Oomah,B.D. ] / J Agric Food Chem   DOI   ScienceOn
28 /
[ Department of Health and Welfare ] / The Industrial Dictionary of Foods
29 /
[ Gerald,F.Combs. ] / The vitamins:Fundamental Aspects in Nutrition and Health
30 Protein measurement with folin phenol reagent /
[ Lowry,O.H.;Rosebrough,N.J.;Farr,A.L.;Randall,R.J. ] / J Biol Chem
31 Antioxidant activity of some spice essential oils on linoleic acid oxidation in aqueous media /
[ Farag,R.S.;Badei,A.Z.M.A.;Hawedi,F.M.;Elbaroty,G.S.A. ] / JAOCS   DOI
32 Bioactive ingredients:antioxidants and polyphenols in tea /
[ Dreosti,I.E. ] / Nutr Rev
33 Age-dependent changes in lipid peroxide levels in the lipoprotein fractions of human serum /
[ Hagihara,M.;Nishigaki,I.;Maseki,M.;Yagi,K. ] / J Gerontology   DOI   ScienceOn
34 The effect of crude drugs on experimental hypercholesterolemia:mode of action of (-)-epigallocatechin gallate in tea leaves /
[ Chisaka,T.;Matsuda,H.;Kubomura,Y.;Mochizuki,M.;Yamahara,J.;Fujimura,H. ] / Chem Pharm Bull   DOI   ScienceOn
35 Effects of Green Tea Catechins on the Lipid Peroxidation and Superoxide Dismutase /
[ Kang,W.S.;Lee,Y.H.;Chung,H.H.;Kang,M.K.;Kim,T.J.;Hong,J.T.;Yun,Y.P. ] / J Fd Hyg Safety   과학기술학회마을
36 Simultaneous determination of œ-tocopherol and retinol in plasma or red cells by high pressure liquid chromatography /
[ Bieri,G.;Tolliver,J.J.;Catignani,G.L. ] / Am J Clin Nat
37 Inhibition of oxidation of human low-density lipoproteins by phenolic substances in different essential oils varieties /
[ Teissedre,P.L.;Waterhouse,A.l. ] / J Agric Food Chem   DOI   ScienceOn
38 /
[ Sim,J.E. ] / Graduate Sch.master's thesis
39 Effect fo Dried Leaf Powders and Ethanol Extracts of Persimmon, Green Tea and Pine Needle on Lipid Metabolism and Antioxidative Capacity in Rats /
[ Kim,E.S.;Kim,M.K. ] / Korean J Nutrution   과학기술학회마을
40 Herbs, Spices and Medical Plants /
[ Mann,C.;Staba,E. ] / Recent Advances in Botany, Horticulture and Pharmacology
41 Isocratic nonaqueous reversed-phase liquid chromatography of carotenoids /
[ Nelis,H.J.;De,Leenheer,A.P. ] / Anal Chem   DOI
42 Free-radical mechanisms in tissue injury /
[ Slater,T.F. ] / Biochem J
43 /
[ Bourne,L.C.;Rice-Evans,C.A.;Lester(ed.) ] / Detecting and measuring bioavailability of phenolics and flavonoids in human:pharmacokinetics of urinary excretion of dietary ferulic acid In:Method in Enzymology; 'Oxidants and Antioxidants
44 Flavonoids and Phenolic Acids of Sage:Influence of some Agricultural Factors /
[ Areias,F.;Valentao,P.;Andrade,P.B.;Ferreres,F.;Seabra,R.M. ] / Agric Food Chem   DOI   ScienceOn
45 Nutritional and Health Aspects of Food Antioxidants /
[ Deshpande,S.S.;Deshpande,U.S.;Salunkhe,D.K.;Madhavi,D.L.;Deshpande,S.S.;Salunkhe,D.K.(eds.) ] / Food Antioxidants.
46 Isolation and structural elucidation of two new glycosides from sage /
[ Wang,M.;Kikuzaki,H.;Zhu,N.;Sang,S.;Nakatani,N.;Ho,C.T. ] / J Agric Food Chem   DOI   ScienceOn
47 The role of antioxidant vitamins in preventing cardiovascular disease and cancers /
[ Hercberg,S.;Galan,P.;Preziosi,P.;Alfarez,M.;Vazquez,C. ] / Nutrition   DOI
48 /
[ Yagi,K ] / Assay for Blood Plasma or Serum:in Methods in enzymology   DOI
49 Progress in essential oil /
[ Lawrence,M.B.;Tobacco,R.J.R. ] / Perfumer and Flavorist
50 Preventive effects of green tea against oxidative damage and mutagenesis /
[ Iso,T.;Yoshiyuki,N.;Mitsuaki,S.;Junichi,W.;Shinji,M.;Naho,SKyoji,Y. ] / Proceedings of the 2nd International Symposium on Green Tea
51 Investigation of the effect of chamazulene on lipid peroxidation and free radical processes /
[ Rekka,E.A.;Kourounakis,A.P.;Kourounakis,P.N. ] / Res Commun Mol Pathol Pharmacol
52 Antioxidative activity and phenolic composition of pilot-plant and commercial extracts of sage and rosemary /
[ Cuvelier,M.E.;Richard,H.;Berset,C. ] / J Am Oil Chem Soc   DOI   ScienceOn
53 /
[] / The Guide to Hygienic Experimental Method
54 Effects of Aquous Green Tea Extracts with œ-tocopherol and Lecithin on the Lipid metabolism in Serum and Liver of Rats /
[ Chung,C.h.;Yoo,Y.S. ] / Korean J Nutrition   과학기술학회마을
55 Redox cycling of iron and lipid peroxidation /
[ Minto,G.;Aust,S.D. ] / Lipid   DOI   ScienceOn
56 The research and Prospect of natural antioxidants /
[ Shin,D.H. ] / Bulletin of Food Technology
57 Effect of vitamin C on glycosylation of protein /
[ Davie,S.J.;Could,B.J.;Yudkin,J.S. ] / Diabetes   DOI   ScienceOn
58 Suppression of genotoxicity of carcinogens by(-)-epigallocatechin gallate /
[ Hayatsu,H.;Inada,N.;Kakutani,T.;Armoto,S.;Negishi,T.;Mori,K.;Okuta,T.;Sakata,I. ] / Prev Med   DOI   ScienceOn
59 /
[ AOAC international USA ] / Offical methods of analysis (16th.Ed.)
60 Carotenes /
[ Kaplan,L.A.;Pesce,A.J,;Kaplan,L.A. ] / Methods in Clinical Chemistry
61 The nutritional status of Antioxidant vitamins relation to serum MDA level in Postmenopausal Women /
[ Jung,K.A.;Kim,S.Y.;Choi,Y.J.;Woo,J.I.;Chang,Y.K. ] / Korean J Nutrition   과학기술학회마을
62 Pharmacological investigation with compounds of chamazulene and matricine /
[ Jakovlev,V.;Issac,O.;Flaskamp,E. ] / Planta Med   DOI   ScienceOn
63 The Science of Green Tea /
[ Shin,M.K. ] / Korean J Dietary Culture
64 /
[ Jadhav,S.J.;Nimbalkar,S.S.;Kulkarni,A.D.;Madhavi,D.L.;Madhavi,D.L.;Deshpande,S.S.;Slunkhe,D.K.(eds.) ] / Lipid Oxidation in Biological and Food Systems.In:Food Antioxidants
65 Determination of total, soluble and insoluble dietary fiber in food-enzymetic gravimatric method /
[ lee,S.C.;Prosky,L.;De,Vries,J.W. ] / MES-TRIS buffer:Collaborative study.J Assoc off Anal Chem
66 Effects of Green Tea Catechin on the Superoxide Dismutase, Glutathione Peroxidase and Xanthine Oxidase Activities of Kidney in Diabetic Rats /
[ Rhee,S.J.;Choi,J.H. ] / Korean J Nutrution   과학기술학회마을