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Effects of Wax Guard on Weight, Triglyceride, Leptin and Fat Cell Size in Rats Fed on a High Fat Diet  

강금지 (덕성여자대학교 자연과학대학 식품영양학과)
임숙자 (덕성여자대학교 자연과학대학 식품영양학과)
정종길 (동신대학교 한의과 대학)
한혜경 (덕성여자대학교 자연과학대학 식품영양학과)
최성숙 (덕성여자대학교 자연과학대학 식품영양학과)
김명화 (덕성여자대학교 자연과학대학 식품영양학과)
권소영 (덕성여자대학교 자연과학대학 식품영양학과)
Publication Information
Journal of Nutrition and Health / v.36, no.5, 2003 , pp. 446-451 More about this Journal
Abstract
The purpose of this study was to investigate the effects of wax gourd on weight, triglyceride, leptin and fat cell size in rats fed a high-fat diet. Male Sprague Dawley rats were fed an experimental diet containing total dietary fat at 40% of calories with wax gourd 0%, 5%, 10% and 15% (w/w) for 4 weeks. Weight gain and triglyceride level fell significantly in the 15% wax gourd group compared to the control group. Epididymal fat pad, abdominal fat and perirenal fat tended to decrease in the 15% wax gourd group. Leptin and free fatty acid level were not significantly different among the groups. Fat cell size significantly decreased in the 10% and 15% wax gourd groups compared to the control group. Weight gain correlated positively with visceral fat masses and the levels of leptin and triglyceride. Fat cell size significantly correlated with visceral fat and leptin level. Therefore, the 15% wax gourd diet substantially reduced weight, triglyceride and fat cell size. (Korean J Nutrition 36(5): 446∼451, 2003)
Keywords
obesity; wax gourd; leptin; triglyceride; fat mass; fat cell size;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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1 Leptin rapidly lowers food intake and elevates metabolic rats in lean ob/obmice /
[ Mistry,A.M.;Swick,A.G.;Romos,D.R. ] / J Nutr
2 Complications of obesity /
[ Bray,G.A. ] / Annals of Internal Medicine   DOI   ScienceOn
3 Dietary conjugated linoleic acid did not affect on body fatness,fat cell sizes and leptin levels in Male sprague Dawley rats /
[ Kang,K.J.;Kim,K.H.;Park,H.S. ] / Nutritional Sciences   과학기술학회마을
4 Effect of total starvation on body composition, serum leptin and lipid profile, and urinary of minerals in women /
[ Lee,E.O. ] / Master Thesis
5 A study on the weight loss effect of wax gourd and the development of processed food from wax gourd /
[ Hong,S.S.;Choi,S.Y.;Cha,S.K.;Kim,H.J.;Park,H.J.;Lee,Y.S. ] / Korea Food Development institute Report
6 /
[] / National nutrition survey report
7 Anthropometric, computed tomography and fat cell data in obese population:relationship with insulin, leptin, tumor necrosis factor-alpha, sex homone-binding globulin and sex hormones /
[ Garaulwt,M.;Perex-Llamas, F.;fuente,T.;Zamora,S.;Tebar,F.J. ] / Euporean J Endo Nov
8 /
[ Korean Nutrition Society ] / Recommended Dietary Allowances for koreans.(7th ed.)
9 Associations between insulin sensitivity and free fatty acid and triglyceride and triglyceride metabolism independent of uncomplicated obesity /
[ Bruce,R.;Godsland,I.;Walton,C.;Crock,D.;Wynn,V. ] / Metabolism Oct   DOI   ScienceOn
10 Cause of obesity /
[ Huh,K.B. ] / Korean J Nutr
11 Dietary fish oil modify adipocytes structure and function /
[ Parrish,C.C.;Pathy,D.A.;Parkers,J.G.;Angel,A. ] / J Cell Physiol   DOI
12 /
[] / National nutrition survey report
13 Leptin secretion from subcutaneous and visceral tissue in women /
[ Van Harmelen, V.;Reynisdottir,S.;Eriksson,P.;Thorne,A.;Hoffstedt,J.;Lonnqvist,F.;Arner,P. ] / Diabetes Jun   DOI   ScienceOn
14 Leptin:Products of the obese gene /
[ Behme,M.T. ] / Nutrition Today   DOI   ScienceOn
15 Markers of triglyceride rich lipoprtein remnant metabolism in vesceral obesity /
[ Chan,D.C.;Watts,G.F.;Barrett,P.H.;Mamo,J.C.;Redgrave,T.G. ] / Clinical Chemistry Feb
16 /
[ Huh,J. ] / The Handbook of Oriental Medicine
17 Effect of conjugated linoleic acid on fat pad weights and celluarity in Sprague Dawley and Zucker rats /
[ Sisk,M.;Azin,M.J.;Hausman,D.B.;Jewell,D.E. ] / FASEB
18 The adipocyte:Storage depot or node on the energy information superhighway /
[ Flier,J.S. ] / Cell   DOI   ScienceOn
19 Obesity Solutions:report of a Meeting /
[ Albu,J.;Allison,D.;Boozer,C.N.;Heymsfield,S.;Kissileff,H.;Kretser,A.;Krumhar,K.;Leibel,R.;Nonas,C.;Pi-Sunyer, X.;Vanltalline,T.;Wedral,E. ] / Nutr Rev   DOI   ScienceOn
20 Mlulti-factorial of obesity:implications for prevention /
[ Grundy,S.M. ] / Am J Clin Nutr
21 In vivo regulation of lipolysis in humans /
[ Coppack,S.W.;Jenson,M.D.;Miles,J.M. ] / J lipid Res
22 Serum immunoreactive-leptin concentrations in normal weight and obese humans /
[ Considine,R.V.;Sinha,M.K.;Heiman,M.L.(et al.) ] / N Engl J Med   DOI   ScienceOn
23 Role of adipose tissue in body-weight regulation:mechanism regulating leptin production and energy blance /
[ Havel,P.J. ] / Proc Nutr Soc   DOI   ScienceOn
24 The Encyclopedia of Crops in Korea /
[ Song,H.S. ] / Pulkotnamoo
25 Influence of body fat distribution on free fatty acid metabolism in obesity /
[ Jenson,M.D.;Haymond,M.W.;Rizza,R.A.;Cryer, Pe.;Miles,J.M. ] / J Clin Invest   DOI
26 /
[ Ahn,D.G. ] / The Encyclopedia of Crops in Korea
27 /
[] / National nutrition survey report
28 Increased hepatic VLDL secretion, lipoproteins and SREBP-1 expression in the corpulent JCRLA-CP rat /
[ Elam,M.B.;Wilcox, Hg.;Cagen,L.M.;Deng,X.;Raghow,R.;Kumar,P.;Heimberg,M.;Russell,J.C. ] / J Lipid Res Dec