In vitro Release Characteristics of Nitroglycerin from Microemulsion-Based Hydrogel System for Anal Fissure Treatment |
Lee, Sang-Kil
(Department of Pharmaceutical Engineering, Inje University)
Shin, Hyun-Woo (College of Pharmacy, Chung-Ang University) Kang, Myung-Joo (College of Pharmacy, Chung-Ang University) Cho, Seong-Wan (Department of Pharmaceutical Engineering, Konyang University) Cho, Jae-Youl (School of Bioscience and Biotechnology, Kangwon National University) Lee, Jae-Hwi (College of Pharmacy, Chung-Ang University) Choi, Young-Wook (College of Pharmacy, Chung-Ang University) |
1 | U. Elkayam, F. Bitar, M. W. Akhter, S. Khan, S. Patrus and M. Derakhshani, Intravenous nitroglycerin in the treatment of decompensated heart failure: potential benefits and limitations, Cardiovasc. Pharmacal. Ther., 9, 227-241. (2004) DOI |
2 | S. A. Imtiaz, J. B. Karen and M. Andrew, Impact of preoperative intravenous nitroglycerin on in-hospital outcomes after coronary artery bypass grafting for unstable angina, Am. Heart J., 148, 727-732 (2004) DOI ScienceOn |
3 | U. Stenestrand, J. Lindback and L Wallentin, Hospital therapy traditions influence long-term survival in patients with acute myocardial infarction, Am. Heart J., 149, 82-90 (2005) DOI ScienceOn |
4 | Merck index 11th Ed., Merck&Co. Inc., Rahway, N.J. U.S.A pp. 1045 (1989) |
5 | http://en.wikipedia.org/wiki/Nitroglycerin |
6 | M. R. Nabih and M. B. Thomas, New and future migraine therapy, Pharmacal. Ther., 112, 199-212 (2006) DOI ScienceOn |
7 |
R. A. Kloner, Pharmacology and Drug Interaction Effects of the Phosphodiesterase 5 Inhibitors: Focus on |
8 | A. MacLean, Chemical Sphincterotomy in the treatment of anal fissure, J. Gastro. Surg., 10, 629-630 (2006) DOI ScienceOn |
9 | R. S. McLeod and J. Evans, Symptomatic care and nitroglycerin in the management of anal fissure, J. Gastrointest. Surg., 6, 278-280 (2002) DOI ScienceOn |
10 | M. J. Utzig, A. J. Kroesen and H. J. Buhr, Concepts in pathogenesis and treatment of chronic anal fissure-A review of the literature, Am. J. Gastroenterol., 98, 968-974 (2003) |
11 | I. Lindsey, O. M. Jones, C. Cunningham and N. J. M. Mortensen, Chronic anal fissure, Br. J. Surg., 91, 270-279 (2004) DOI ScienceOn |
12 | USP NF 23rd Ed., The United States Pharmacopeial Convention Inc., U.S.A. pp. 1090 (1994) |
13 | U. Thadani and T. Rodgers, Side effects of using nitrates to treat angina., Expert. Opin. Drug Saf Expert., 5, 667-674 (2006) DOI ScienceOn |
14 | A. C. Sintov and L. Shapiro, New microemulsion vehicle facilitates percutaneous penetration in vitro and cutaneous drug bioavailability in vivo, J. Controlled Rel., 95, 173-183 (2004) DOI ScienceOn |
15 | M. R. Gasco, M. Gallarate, M. Trotta, L. Bauchiero, E. Gremmo and O. Chiappero, Microemulsions as topical delivery vehicles: ocular administration of timolol, J. Pharm. Biomed. Anal., 7, 433-439 (1989) DOI ScienceOn |
16 | M. Trotta, M. R. Gasco and S. Morel, Release of drugs from oil-water microemulsions, J. Controlled Rel., 10, 237-243 (1989) DOI ScienceOn |
17 | P. P. Constantinides, Lipid microemulsion for improving drug dissolution and oral absorption: physical and biopharmaceutical aspects, Pharm. Res., 12, 1561-1570 (1995) DOI |
18 | P. Spiclin, M. Homar, A. Zupani- Valant and M. Gasperlin, Sodium ascorbyl phosphate in topical microemulsions, Int. J. Pharm., 256, 65-73 (2003) DOI ScienceOn |
19 | E. A. Mueler, F. M. Kovarik, J. B. van Bree, W. Tetzloff, J. Grevel and K. Kutz, Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation, Pharm Res., 11, 301-304 (1994) DOI |
20 | A. C. Sintov and S. Botner, Transdermal drug delivery using microemulsion and aqueous systems: Influence of skin storage conditions on the in vitro permeability of diclofenac from aqueous vehicle systems, Int. J. Pharm., 311, 55-62 (2006) DOI ScienceOn |
21 | M. Trotta, Influence of phase transformation on indomethacin release from microemulsions, J. Controlled Rel., 60, 399-405 (1999) DOI ScienceOn |
![]() |