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http://dx.doi.org/10.4333/KPS.2007.37.2.113

Microencapsulation of Fish Oil by Spray Drying using Different Wall Materials  

Cha, Kwang-Ho (College of Pharmacy, Chungnam National University)
Yang, Jin-Su (College of Pharmacy, Chungnam National University)
Yeon, Seung-Ho (RM315 TBI Center, Chungnam National University)
Hong, Jang-Hwan (RM315 TBI Center, Chungnam National University)
Kim, Min-Soo (College of Pharmacy, Chungnam National University)
Kim, Jeong-Soo (College of Pharmacy, Chungnam National University)
Hwang, Sung-Joo (College of Pharmacy, Chungnam National University)
Publication Information
Journal of Pharmaceutical Investigation / v.37, no.2, 2007 , pp. 113-117 More about this Journal
Abstract
The aim of this study was to investigate the effect of different wall material on the microencapsulation efficiency of microcapsules containing fish oil. The present work reports on the microencapsulation of fish oil by spray drying using hydroxypropyl methylcellulose (HPMC) 2910, maltodextrin, gelatin, sodium caseinate as wall materials. The emulsion stability was assessed by emulsion stability index value (ESI). The microstructural properties of microcapsules was evaluated by scanning electron microscopy (SEM) and microencapsulation efficiency (ME) was assessed by soxhlet method. The highest ESI and ME were observed in the case of a 1:1 gelatin/sodium caseinate ratio and 1:1 glycerin fatty acid ester/lecithin ratio, and ME of microcapsules was increased with increasing the ESI of emulsion. Thus, the stability of emulsion was a critical factor for the encapsulation of fish oil.
Keywords
Fish oil; Microencapsulation; Spray drying;
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