Preparation and Characterization of Liquefied Ibuprofen Using Self-Microemulsion Drug Delivery System (SMEDDS)
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Ahn, Yong-San
(Department of Polymer.Nano Science and Technology, Chonbuk National University)
Song, Ji-Hee (Department of Polymer.Nano Science and Technology, Chonbuk National University) Kang, Bok-Ki (Department of Polymer.Nano Science and Technology, Chonbuk National University) Kim, Moon-Suk (Nanobiomaterials Laboratory, Korea Research Institute of Chemical Technology) Cho, Sun-Hang (Nanobiomaterials Laboratory, Korea Research Institute of Chemical Technology) Rhee, John-M. (Department of Polymer.Nano Science and Technology, Chonbuk National University) Lee, Hai-Bang (Nanobiomaterials Laboratory, Korea Research Institute of Chemical Technology) Khang, Gil-Son (Department of Polymer.Nano Science and Technology, Chonbuk National University) |
1 | C.S. Yong, S.H. Jung, S.M. Park, 1D. Rhee and H.G. Choi, Enhanced solubility of ibuprofen with poloxamer and mentol, J. Kor. Pharm. Sci., 33, 57-60 (2003) |
2 | J.W. Lee, E.S. Park and S.C. Chi, Solubilization of ibuprofen in aqueous solution, J. Kor. Pharm. Sci., 27, 279286 (1997) |
3 | P. Santi, S. Nicoli, G. Colombo, R Bettini, M. Artusi, S. Rimondi, e. Padula, P. Rizzo and P. Colombo, Post-iontophoresis transport of ibuprofen lysine across rabbit ear skin, Int. J Pharm., 266,69-75 (2003) DOI ScienceOn |
4 | A.A. Bousfiha, A Maaroufi, A Abid and S. Tahiri, Antipyretique activity of ibuprofen syrup in children emergency unit, J. de Pediatrie et de Puericulture., 16, 407-410 (2003) DOI ScienceOn |
5 | S. Schiermeier and P.e. Schmidt, Fast dispersible ibuprofen tablets, Eur. J. Pharm. Sci., 15, 295-305 (2002) DOI ScienceOn |
6 | M.K Ghorab and M.C. Adeyeye, Enhancement of ibuprofen dissolution via wet granulation with beta-cyclodextrin, Pharm. Dev. Technol., 6, 305-314 (1994) DOI ScienceOn |
7 | F.K Glowka, Stereoselective pharmacokinetics of ibuprofen and its lysinate from suppsitiories in rabbits, Int. J. Pharm., 199, 159-166 (2000) DOI ScienceOn |
8 | Y.E. Nashed and AK Mitra, Synthesis and characterization of novel dipeptide ester prodrugs of acyclovir, Spectrochi. Acta, Part A: Molec. Biomolec. Spectroscopy, 59, 2033-2039 (2003) DOI ScienceOn |
9 | P. Jolimaftre, M. Malet-Martino and R Martino, Fluorouracil prodrugs for the treatment of proliferative vitreoretinopathy : Formulation in silicone oil and in vitro release of fluorouracil, Int. J. Pharm., 259, 181-192 (2003) DOI ScienceOn |
10 | R.H. Christopher, 1H. Porter, G.A. Edwards, A Miillertz, H.G. Kristensen and W.N. Charman, Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides, Eur. 1. Pharm. Sci., 20, 91-97 (2003) DOI ScienceOn |
11 | H.J. Kil, S.H. Cho, G. Khang, S.Y Jeung, KS. Seo, B.Y Yoon, B. K Kang and H.B. Lee, Preparation of solid dosage form containing SMEDDS of simvastatin by microencapsulation, J. Kor. Pharm. Sci., 33, 121-127 (2003) |
12 | R Arley, Physician's Desk Reference, Medical Economics Company, 53, 875-889 (1999) |
13 | H.S. Kim, S.K Lee, S.u. Choi, H.S. Park, H.J. Jeon and YW Choi, Improved dissolution characteristics of ibuprofen employing self-microemulsifying drug delivery system and their bioavailability in rats, J. Kor. Phann. Sci., 32, 27-33 (2002) |
14 | M. Maheshwari, AR Ketkar, B. Chauhan, v.B. Patil and AR Paradkar, Preparation and characterization of ibuprofen cetyl alcohol beads by melt solidification technique : Effect of variables, Int. J. Pharm., 261, 57-67 (2003) DOI ScienceOn |
15 | L.M Prince, A theory of aqueous emulsion. I. Negative interfacial tension at the. oil/water interface, J. Colloid Inteiface Sci., 23, 165-173 (1967) DOI ScienceOn |
16 | K. Shinoda and S. Friberg, Microemulsions. Colloidal aspects., Adv. Colloid Inteiface Sci., 4, 281-300 (1975) DOI ScienceOn |
17 | J. Tabony, Formation of cubic structures in microemulsions containing equal volumes of water and oil, Nature, 319, 400 (1986) DOI |
18 | D. Attwood, C. Mallon and C.J. Taylor, A study on factors influencing the droplet size in nonionic oil-in-water microemulsions, Int. J. Pharm., 88, 417-422 (1992) DOI ScienceOn |
19 | P. Fini, M.L. Curri, M. Castagnolo, E Ciampi and A. Agostiano, Calorimetric study of CdS nanoparticle formation in wlo microemulsions, Mater. Sci. Eng., 23, 1077-1081 (2003) DOI ScienceOn |
20 | T.P. Shakhtshneider, M.A. Vasiltchenko, A.A. Politov and V.V. Boldyrev, The me chanochemical preperation of solid disperse system of ibuprofen-polyethylene glycol, Int. J. Pharm., 130, 25-32 (1996) DOI ScienceOn |
21 | R. Aboofazeli, C.B. Lawrence, S.R. Wicks and MJ. Lawrence, Investigations into the formation and characterisation of phospholipid microemulsions. III. Pseudo-ternary phase diagrams of systems containing water-lecithin-isopropyl myristate and either an alkanoic acid, amine, alkanediol, polyethylene gylcol alkyl ether or alcohol as cosurfactant, Int. J. Pharm., III, 63-72 (1994) |
22 | J.K. Jeong, G. Khang, J.M. Rhee, H.C. Shin and H.B. Lee, Effect of molecular weights and mixture ratios of polyvinylpyrrolidone on the bioavailability of ipriflavone solid dispersion, J. Kor. Pharm. Sci., 30, 235-239 (2000) |
23 |
L.A Hergert and G.M. Escandar, Spectrofluorimetric study of the |
24 |
Y.B. Lee, I.C. Oh, 1K Park and S.c. Shin, Inclusion complex of analgesic and antiinflammatory agents with cyclodextrins (1) : Enhancement of dissolution of ibuprofen by |
25 | P.S. Khiew, N.M. Huang, S. Radiman and S. Ahmad, Synthesis of NiS nanoparticles using a sugar-ester nonionic water-in-oi1 microemu1sion, Materials Letters, 58, 762-767 (2004) DOI ScienceOn |
26 | IH. Yang, YI. Kim, HJ. Kim and KH. Chung, Preparation and characterization of microemulsion containing ibuprofen, J. Kor. Phann. Sci., 45, 634-640 (2001) |
27 | D. Attwood, e. Mallon and CJ. Taylor, Phase studies of oil-inwater phospholipod microemulsions, Int. J. Pharm., 84, RS-R8 (1992) |
28 | D. Langevin, Microemulsions-interfacial aspects, Adv. Colloid Inteiface Sci., 34, 583-595 (1991) DOI ScienceOn |
29 | C.W Pouton, Self-emulsifying drug delivery system : Assessment of the efficiency of emulsification, Int. J. Phann., 27,335-348 (1985) DOI ScienceOn |
30 | R.M. Evans and S.J. Farr, The development of novel, pressurised aerosols formulated as solutions, J. Biophann. Sci., 3, 33-40 (1992) DOI ScienceOn |
31 | R. Aboofazeli, N. Patel, M. Thomas and MJ. Lawrence, Investigations into the formation and characterization of phospholipid microemulsion IV. Pseudo-ternary phase diagrams of systems containing water-lecithin-alcohol and oil; The influence of oil, Int. J. Pharm., 125, 107-116 (1995) DOI ScienceOn |
32 | S.A. Charman, W.N. Charman, M.C. Rogge, T.D. Wilson, F.J. Dutko and C.W. Pouton, Self-emulsifying drug delivery system : Formulation and biopharmaceutical evaluation of an investigational lipophilic compound, Pharm. Res., 9, 87-93 (1992) DOI ScienceOn |
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